A prospective study evaluating utility of Mannheim peritonitis index in predicting prognosis of perforation peritonitis

Sharma, Rajesh; Ranjan, Vikrant; Jain, Shubham; Joshi, Tulika; Tyagi, Anurag; Chaphekar, Rohan

doi:10.4103/0976-9668.166076

Cited by 13 publications

(7 citation statements)

References 10 publications

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“…Rajendra Singh Jhobta et al (Kumar et al, 2017), in their study, observed 84% of males as the majority for Perforation Peritonitis. Similarly, Ranjan et al (2015) found 52% males and 48% females. Moreover, Rodolfo L et al, in their investigation seen that appendicular perforations were 48.28% while among 2.87% cases, gastric pathology and small bowel pathology were available and colonic pathology was found among 2.30%.…”

Section: Literature Reviewmentioning

confidence: 86%

“…Demographic data such as gender, age, aetiology of peritonitis, and hospitalization days were (Jhobta et al, 2006) Diffuse: 83% Localised: 17% (Ranjan et al, 2015) Diffuse: 34.49 % Localised: 65.5% also collected from cases. Investigations such as complete blood count, biochemical analysis of blood, microbiology for serology, X-ray of erect abdomen, CT scan (abdomen/pelvis) / ultrasonography (abdomen/pelvis) were carried out wherever necessary.…”

Section: Source Of Data and Sample Sizementioning

confidence: 99%

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MPI score assessment of perforation peritonitis patients

Saygaonkar

Nerlekar

2020

ijrps

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The most widespread clinical emergency in India is perforation peritonitis. Following improvements in operational procedures, antimicrobial treatments, and care in ICUs, peritonitis control is often very complicated, complicated, and challenging. MPI provides the highest precision of risk-assessment such that specific predictions for patients with peritonitis could be estimated. The objective of this research is to determine the prognosis for perforated peritonitis patients using the peritonitis index from Mannheim. It is also targeted at a) assessing the results in Mannheim peritonitis test perforation cases b) evaluating elevated incidents of perforated peritonitis on the Peritonitis Scale with Mannheim. C) Determining the function of the Mannheim Peritonitis Index in decision-making on peritonitis surgery. This research measured the diagnosis of perforated peritonitis patients utilizing peritonitis score of Mannheim’s Index. In the present study, we observed that the majority of the study subjects were males (65.38%), and many of the cases ranged from the age group of 46-55 years (25%), as well as 36-45 years (23.07%). The majority of the cases had duodenal perforation (42.30%), followed by gastric perforation (28.84%), appendicular perforation (13.46%), filial perforation (9.61%), jejunal (3.8%), colonic perforation (1.9%). We observed that the majority of the study subjects reported the MPI score between 21-29 (46.15%), followed by (38.46%) cases who reported MPI score of more than 29, and 15.38% who reported MPI score less than 21.

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Section: Literature Reviewmentioning

confidence: 86%

Section: Source Of Data and Sample Sizementioning

confidence: 99%

MPI score assessment of perforation peritonitis patients

Saygaonkar

Nerlekar

2020

ijrps

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“…Independent study variables for MPI scoring system included: age in completed years, sex, malignancy (present/absent), organ failure (present/absent), evolution time (>24 hours/<24 hours), extension of peritonitis (localized/diffuse), origin of sepsis (noncolonic/colonic), character of exudates (clear/faecal/purulent) as described previously (12)(13)(14). We also curated available published data of MPI based studies from India for our comparative analysis (17)(18)(19)(20)(21)(22)(23)(24)(25)(26).…”

Section: Study Detailsmentioning

confidence: 99%

“…We utilized an 8-parameter-based scale deployed in all studies for assessing MPI scores as described in study detail. In order to understand the prevalence and pattern of secondary peritonitis across India, we compared our in-house study with 10 other published studies that had used MPI scoring system from various states of India (17)(18)(19)(20)(21)(22)(23)(24)(25)(26). Studies from different geographical locations were selected to have an idea about the epidemiological diversity of secondary peritonitis across India (Figures 1A, 1B).…”

Section: Occurrence and Associated Mortality Due To Secondary Periton...mentioning

confidence: 99%

“…MPI based system is often advantageous over other scoring systems for better management of the disease, patient segregation, prognostic reliability and specificity (15,16). Additionally, we performed a comparative analysis of studies with secondary peritonitis throughout India using MPI based scoring parameters and provided a bird's eye view regarding risk factors of the disease (17)(18)(19)(20)(21)(22)(23)(24)(25)(26). The purpose of the study was to understand the variability in outcome due to MPI score parameters across Indian patients with diverse background and predict the overall effectiveness of the MPI scoring system used for accessing risk groups in secondary peritonitis.…”

Section: Introductionmentioning

confidence: 99%

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A comparative analytical study on outcome of secondary peritonitis using Mannheim’s peritonitis index in geographically diverse Indian patients

Ghosh,

Halder,

Sen

et al. 2023

Turk J Surg

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Objective: Secondary peritonitis is caused by infection of the peritoneal cavity due to perforation of the alimentary tract. Mannheim’s peritonitis ındex (MPI) is a prognostic scoring system that predicts outcomes in peritonitis. Increasing MPI scores correlate with poor outcomes and mortality. The objective of this study is to evaluate the effectiveness of MPI-based prognosis and its impact on Indian patients with secondary peritonitis. Material and Methods: For understanding the effectiveness of the MPI scoring system, a cross-sectional data analysis of published studies on secondary peritonitis from 10 geographical locations in India was performed. The 10-site study results were compared with unpublished in-house study data for individual MPI parameters to analyze any variations of MPI score-based predictions across a diverse Indian population. Patients were divided into risk groups on the basis of MPI scores: <21 mild, MPI= 21-29 moderate, MPI> 29 severe risk. Results: We observed a significant correlation between mortality with age and gender as reported worldwide. Site of perforations were prevalent in the upper alimentary tract with the majority being gastro-duodenal for the Indian population as opposed to distal parts in the western population. Higher lethality in India is often associated with evolution time, organ failure, and sepsis due to delayed presentation and poor management. Conclusion: MPI scoring is effective in predicting risk across geographically diverse Indian populations. The sensitivity and specificity of MPI scores are more reliable and a score >29 specifically recommends aggressive resuscitation & monitoring of patients, initiation of broad-spectrum antibiotics, and intensive care support to reduce mortality and morbidity.

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Sarcopenia discriminates poor prognosis in elderly patients following emergency surgery for perforation panperitonitis

Kubo

Kawanaka

Hiroshige

et al. 2019

Annals of Gastroent Surgery

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AimSarcopenia has been reported as a prognostic predictor in various conditions; however, it has not been examined in patients with perforation panperitonitis.MethodsA total of 103 consecutive patients with perforation panperitonitis who underwent emergency surgery from 2008 to 2016 were retrospectively evaluated. Skeletal muscle index (SMI) was measured as the cross‐sectional area (cm2) of skeletal muscle in the L3 region on computed tomography images normalized for height (cm2/m2). Sarcopenia was defined as an SMI of ≤43.75 and ≤41.10 cm2/m2 in men and women, respectively. The impact of sarcopenia on postoperative outcomes was investigated.ResultsSarcopenia was present in 50 (48.5%) patients. Severe complications (Clavien‐Dindo grade ≥IIIb) and in‐hospital mortality were more frequently observed in patients with than without sarcopenia (28.0% vs 9.4%, P = .015) (20.0% vs 5.7%, P = .029) respectively. Multivariate analysis showed that age, sarcopenia, and renal dysfunction were independent risk factors for severe complications and in‐hospital mortality. The optimal cut‐off levels of age and SMI for predicting these were ≥79 years and SMI <38 cm2/m2, respectively. Among the patients aged ≥79 years, those with SMI <38 cm2/m2 had a severe complication rate of 71% and an in‐hospital mortality rate of 57%, whereas the rate of those with SMI ≥38 cm2/m2 was 22% (P = .011) and 11% (P = .008), respectively.ConclusionSarcopenia is a predictive factor of severe complications and in‐hospital mortality following emergency surgery for perforation panperitonitis, especially in elderly patients. Estimation of sarcopenia may identify patients eligible or not eligible for emergency surgery among elderly patients.

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A prospective study evaluating utility of Mannheim peritonitis index in predicting prognosis of perforation peritonitis

Cited by 13 publications

References 10 publications

MPI score assessment of perforation peritonitis patients

MPI score assessment of perforation peritonitis patients

A comparative analytical study on outcome of secondary peritonitis using Mannheim’s peritonitis index in geographically diverse Indian patients

Sarcopenia discriminates poor prognosis in elderly patients following emergency surgery for perforation panperitonitis

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