A Prospective Study of Four Total Ankle Arthroplasty Implants by Non-Designer Investigators

Lefrancois, Tina; Younger, Alastair; Wing, Kevin; Penner, Murray; Dryden, Peter; Wong, Hubert; Daniels, Timothy R.; Glazebrook, Mark

doi:10.2106/jbjs.16.00097

Cited by 60 publications

(38 citation statements)

References 18 publications

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“…Ankle arthroplasty has reemerged as a viable and often preferable option to ankle arthrodesis for patients with endstage ankle disease. 3,[11][12][13] Historically, TAA was associated with early complications and high failure rates. However, the more anatomic designs and improved biomechanical properties of newer generation TAAs have improved these issues and the longevity of the implants.…”

Section: Discussionmentioning

confidence: 99%

Does Patient-Specific Instrumentation Have a Higher Rate of Early Osteolysis Than Standard Referencing Techniques in Total Ankle Arthroplasty? A Radiographic Analysis

Escudero

Symes

Bemenderfer

et al. 2019

Foot & Ankle Specialist

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Introduction: Patient-specific instrumentation (PSI) has been developed for total ankle arthroplasty (TAA), with proven benefits. One concern regarding PSI is the need for more soft tissue dissection in order to accurately position the PSI guides, which has the theoretical disadvantage of increased osteolysis. The purpose of our study is to compare the incidence and magnitude of osteolysis for the INFINITY Total Ankle System between PSI and standard referencing (SR) techniques. Methods: Sixty-seven patients who underwent primary TAA using Prophecy (PSI) or SR technique between 2013 and 2015 were reviewed in a retrospective observational study. Osteolysis was assessed on radiographs at 2 years. The incidence was calculated by binomial distribution. The number of zones compromised and the magnitude of osteolysis was calculated using the median as a summary statistic and interquartile range as dispersion statistic. Fisher exact test was used to compare both groups, then a regression model was estimated to calculate the odds ratio for osteolysis. Results: Of the 67 TAAs, 51 were in the PSI group and 16 in the SR group. In the PSI group the incidence, number of compromised zones (CZ), and magnitude was 41% (25%-59%), 1 [1-2], and 2 [2-3], respectively. In the SR group these were 36% (13%-65%), 3 [2-3], and 3 [2-4], respectively. No significant differences were found ( P = .46, P = .12, P = .33). A slightly higher risk of osteolysis was found in the PSI group (odds ratio = 1.33 [0.36-4.83]) ( P = .46). The majority of lesions were in 1 zone with size of 2 to 5 mm (63% for all cohort, 64% PSI, 60% SR). Two cases underwent revision for aseptic loosening, 1 in the SR group and 1 in the PSI group. Conclusion: According to our data, there is no significant difference between PSI and SR in terms of risk, incidence, size and magnitude of osteolysis in the INFINITY Total Ankle System at 2 years. Levels of Evidence: Therapeutic, Level III, Retrospective cohort study

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Section: Discussionmentioning

confidence: 99%

Does Patient-Specific Instrumentation Have a Higher Rate of Early Osteolysis Than Standard Referencing Techniques in Total Ankle Arthroplasty? A Radiographic Analysis

Escudero

Symes

Bemenderfer

et al. 2019

Foot & Ankle Specialist

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“…However, in terms of adverse events, ankle impingement syndrome was more common in the HINTEGRA group, while intraoperative malleolar fracture was found only in the MOBILITY group [47] . A study demonstrated similar results between HINTEGRA, STAR, and AGILITY implants [48] .…”

Section: Comparative Studiesmentioning

confidence: 65%

Total Ankle Arthroplasty: Long-term Survival and Factors that Influence it

Rodríguez-Merchán

Moracia-Ochagavía

2019

International Journal of Orthopaedics

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“…121 The Agility prosthesis (DePuy, Warsaw, IN) is the most commonly reported 2-component TAA but it was plagued with a high complication rate 23,80,110 despite having reasonable survival compared with other TAAs 95 and similar patient-reported outcomes. 74 Failure was often associated with a syndesmosis nonunion. 64 Newer designs, combined with a better understanding of foot deformity correction with TAA, 27,79 have led to improved clinical results and survival.…”

Section: Resultsmentioning

confidence: 99%

Ankle Arthritis

Veljkovic

Salat

et al. 2019

Foot & Ankle Orthopaedics

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Ankle arthritis is a major source of morbidity impacting a younger working age population than hip and knee arthritis. Unlike the hip and knee, more than 70% of ankle arthritis cases are post-traumatic, with the remainder being inflammatory or primary arthritis. Nonoperative treatment begins with lifestyle and shoe-wear modifications and progresses to bracing, physical therapy, anti-inflammatory medications, and intra-articular injections. Ankle arthrodesis and total ankle arthroplasty are the 2 main surgical options for end-stage ankle arthritis, with debridement, realignment osteotomy, and distraction arthroplasty being appropriate for limited indications.Level of Evidence:Level V, expert opinion.

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A Prospective Study of Four Total Ankle Arthroplasty Implants by Non-Designer Investigators

Abstract: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.

Cited by 60 publications

References 18 publications

Does Patient-Specific Instrumentation Have a Higher Rate of Early Osteolysis Than Standard Referencing Techniques in Total Ankle Arthroplasty? A Radiographic Analysis

Does Patient-Specific Instrumentation Have a Higher Rate of Early Osteolysis Than Standard Referencing Techniques in Total Ankle Arthroplasty? A Radiographic Analysis

Total Ankle Arthroplasty: Long-term Survival and Factors that Influence it

Ankle Arthritis

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