A prospective study of indications for mediastinoscopy in lung cancer with CT findings, tumor size, and tumor markers

Kimura, Hideki; Iwai, Naomichi; Ando, Soichiro; Kakizawa, Kimitaka; Yamamoto, Naoyoshi; Hoshino, Hidehisa

doi:10.1016/s0003-4975(03)00035-3

Cited by 24 publications

(15 citation statements)

References 22 publications

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“…As VM improves visualisation thus facilitating safe dissection, biopsy and haemostasis [5,14,15] it could set the standard of the surgical staging of the mediastinum.…”

Section: Discussionmentioning

confidence: 99%

Does video-mediastinoscopy improve the results of conventional mediastinoscopy?☆

Leschber

Sperling

Klemm

et al. 2008

European Journal of Cardio-Thoracic Surgery

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This study demonstrates that in comparison with CM, VM routinely yields more lymph nodes with fewer complications with a tendency towards better accuracy and negative predictive value. For these reasons, we believe that VM should replace CM as the method of choice. Furthermore VM would allow standardisation, thereby having an advantage in comparison to the less invasive newer staging techniques. This way mediastinoscopy could remain the gold standard despite its invasiveness.

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“…As VM improves visualisation thus facilitating safe dissection, biopsy and haemostasis [5,14,15] it could set the standard of the surgical staging of the mediastinum.…”

Section: Discussionmentioning

confidence: 99%

Does video-mediastinoscopy improve the results of conventional mediastinoscopy?☆

Leschber

Sperling

Klemm

et al. 2008

European Journal of Cardio-Thoracic Surgery

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show abstract

“…Five studies reported 22 FN cases [19][20][21][22][23]. Most FN in VAM studies were due to insufficient lymph node sampling.…”

Section: False-negative Results In Vam Studiesmentioning

confidence: 99%

“…The full text of 65 EBUS articles and 34 VAM articles were evaluated. Finally, 10 studies with 999 EBUS patients [6,[9][10][11][12][13][14][15][16][17] and seven studies with 915 VAM patients [6,[18][19][20][21][22][23] were included in the meta-analysis (Figs. 1, 2).…”

Section: Study Selectionmentioning

confidence: 99%

Comparison of Endobronchial Ultrasound-Guided Fine Needle Aspiration and Video-Assisted Mediastinoscopy for Mediastinal Staging of Lung Cancer

Guan

Han

et al. 2015

Lung

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Video-assisted mediastinoscopy (VAM) and endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) are the two most commonly used invasive methods for mediastinal staging of lung cancer. The objective of this review is to assess and compare the overall diagnostic values of VAM and EBUS-TBNA. PubMed, Embase, Web of Science and the Cochrane Library were searched for studies that evaluated EBUS-TBNA or VAM accuracy. Quantitative meta-analysis was used to pool sensitivity and specificity, and study quality was evaluated. Meta-regression was applied to indirectly compare EBUS-TBNA and VAM after adjusting quality score, study design, and station number. A total of ten studies with 999 EBUS-TBNA patients and seven studies with 915 VAM patients were included. Since the pooled specificity was 100% for both modalities, sensitivity was mainly analyzed. The pooled sensitivities for EBUS-TBNA and VAM were 0.84 (95% CI 0.79-0.88) and 0.86 (95% CI 0.82-0.90), respectively. Subgroup analyses of quality score, study design, station number and rapid on-site cytologic evaluation showed no significant influence on the overall sensitivity of the two modalities. After adjusting quality score, study design, and station number, the pooled sensitivities of VAM and EBUS-TBNA were not significantly different. However, more procedural complications and fewer false negatives (FN) were found with VAM than EBUS-TBNA. VAM and EBUS exhibited equally high diagnostic accuracy for mediastinal staging of lung cancer. Due to lower morbidity with EBUS-TBNA and fewer FN with VAM, EBUS-TBNA should be performed first, followed by VAM in the case of a negative needle result.

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“…We conducted a prospective phase II study using videoassisted mediastinoscopy (VAM) for the selection of candidates for surgery from lung cancer patients who were referred to our Cancer Center between October 1998 and December 2004 [18]. The purpose of this study was to verify the efficacy of indication criteria for VAM as well as to compare the methods of dissection of mediastinal lymph nodes.…”

Section: Methodsmentioning

confidence: 99%

“…The indications for VAM have been stated elsewhere [18]. Briefly, those who had maximum tumor sizes larger than the limits (adenocarcinoma or undefined histology, >2 cm; squamous-cell or large-cell carcinoma, >3 cm; and small-cell carcinoma of any size) received VAM.…”

Section: Indications For Video-assisted Mediastinoscopy (Vam)mentioning

confidence: 99%

Indications for mediastinoscopy and comparison of lymph node dissections in candidates for lung cancer surgery

et al. 2007

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A prospective study of indications for mediastinoscopy in lung cancer with CT findings, tumor size, and tumor markers

Cited by 24 publications

References 22 publications

Does video-mediastinoscopy improve the results of conventional mediastinoscopy?☆

Does video-mediastinoscopy improve the results of conventional mediastinoscopy?☆

Comparison of Endobronchial Ultrasound-Guided Fine Needle Aspiration and Video-Assisted Mediastinoscopy for Mediastinal Staging of Lung Cancer

Indications for mediastinoscopy and comparison of lymph node dissections in candidates for lung cancer surgery

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