A prospective study of serum zinc concentration in children with celiac disease

Naveh, Yehezkel; Lightman, Abraham; Zinder, Oren

doi:10.1016/s0022-3476(83)80248-0

Cited by 22 publications

(16 citation statements)

References 7 publications

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“…In the group of children with untreated coeliac disease, the mean value of plasma zinc concentration (69 gg/dl) was significantly lower than that of the healthy children, which agrees with other studies [9]. In these patients the zinc deficiency may result from (a) the formation of insoluble complexes of zinc and lipids which are not absorbed, (b) exudation of zinc protein complexes into the intestinal lumen, (c) damage to the zinc uptake system of the enterocyte and (d) reduced intake.…”

Section: Discussionsupporting

confidence: 92%

Plasma zinc levels in children with chronic diarrhoea

et al. 1986

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We measured the plasma zinc concentration in a group of children with chronic diarrhoea. Fifteen patients with untreated coeliac disease had a mean plasma zinc level significantly lower than that of healthy children (69 micrograms/dl vs 96 micrograms/dl). In patients with chronic post-enteritic diarrhoea (n = 70) the mean plasma zinc level was in the normal range (100 micrograms/dl). The latter result suggests that our country a secondary zinc deficiency is not a feature of chronic post-enteritic diarrhoea.

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Section: Discussionsupporting

confidence: 92%

Plasma zinc levels in children with chronic diarrhoea

et al. 1986

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“…Zinc may be involved directly in promoting growth with IGF‐1 in children 32 . Zinc deficiencies have been documented in CD, in cases of normal intestinal absorption because of the increased turn over and loss of endogenous zinc 14,33–35 . Zinc supplementation is recommended in CD by some authors for recovery of mucosal integrity in zinc deficiency 14 .…”

Section: Discussionmentioning

confidence: 99%

“…In contrast, zinc deficiency has been well documented in CD and a low serum zinc level is one evidence of multiple deficiencies in absorption in children with CD 11–13 , and zinc supplementation is recommended for mucosal recovery 14 .…”

mentioning

confidence: 99%

Celiac disease with various presentations

Doğanci¹,

Bozkurt

2004

Pediatrics International

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“…In these CD patients, zinc deficiency may result from a cumulative loss of insoluble zinc complexes with fat and phosphate, exudation of zinc protein complexes into the intestinal lumen and massive loss of intestinal secretions or impaired zinc absorption because of injured intestinal epithelial cell membrane. 6 …”

Section: Discussionmentioning

confidence: 99%

“…The aim of the present study was to investigate prospectively the value of measuring plasma zinc levels in the diagnosis of CD in short‐statured children and to determine the sensitivity, specificity and positive and negative predictive values (PPV and NPV, respectively) of zinc for the diagnosis of monosymptomatic CD. Although a review of the literature revealed some reports of zinc deficiency in children with CD as consequence of intestinal malabsorption, 6–8 this seems to be a unique study on the levels of zinc in children with monosymptomatic CD who present with short stature.…”

mentioning

confidence: 95%