A prospective study on drug utilization pattern and rationality in treatment of type II diabetes mellitus: a population based analysis

Brahmbhatt, Shruti; Sattigeri, Bhagya; Nil, Ashok Kumar; Parikh, Devang; Shah, Heena

doi:10.5455/2320-6012.ijrms20140852

Cited by 14 publications

(14 citation statements)

References 16 publications

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“…12 In our study, the male patients were predominated and the same report were also found by Brahmbhatt SV et al, Vengurlekar S et al, Boccuzzi, Yurgin N et al and showed that there occurs male preponderance in the prevalence of diabetes. [14][15][16] Majority of our patients were in the age group of 41-60 years (62.5%) which is in concordance with the earlier published literat. 15,17 Hypertension (37.5%) was the most common co-morbid condition, followed by hypercholesterolemia (11.5%).…”

Section: Discussionsupporting

confidence: 93%

“…However, the prevalence of hypertension has ranged from 31 to 70%. 18,19 In this study 38.5% of patients receiving monotherapy and the same results was also reported by Brahmbhatt SV et al 14 This study showed that metformin was prescribed most frequently, 23 times (57%). Metformin were mainly prescribed in this study as it has been shown to be cost effective in addition to giving the advantage of better compliance.…”

Section: Discussionsupporting

confidence: 86%

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Prescription pattern of anti-diabetic drugs in a rural area of South Malabar region of Kerala, South India

Salim

Mufeeda

2018

Int J Res Med Sci

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Background: Diabetes is a chronic metabolic disease associated with significant morbidity, mortality and cost to the community. This study was conducted to evaluate the prescription pattern of type 2 diabetes mellitus in a rural population scenario including different age groups and gender.Methods: It was a prospective observational study carried out at Pulikkal village, Malappuram from January 2018 to June 2018. One hundred and four patients of Type II diabetes mellitus who confirmed to the speciﬁed inclusion and exclusion criteria were enrolled for the study after taking consent.Results: This study shown that 62.5% of patients were on the age group of 41 to 60 and 96% of these patients were literate. This study shown that mono therapy was observed in 38.46% patients and combination therapy in 61.54% patients and metformin as the predominantly prescribed oral anti diabetic drug both in combination and monotherapy. In the sulfonylureas, glimepiride followed by glipizide were the prominently prescribed drugs. There is also a significant increase in the prescriptions of newer OHAs like thiazolidinedione’s, alpha glucosidase inhibitors and DPP-4 inhibitors.Conclusions: Metformin is the most prescribed anti-diabetic drug in monotherapy. In combination therapy, most frequently prescribed combination was the glimepiride and metformin and followed by metformin+glipizide and glibenclamide and metformin.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 86%

Prescription pattern of anti-diabetic drugs in a rural area of South Malabar region of Kerala, South India

Salim

Mufeeda

2018

Int J Res Med Sci

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“…For the treatment of T2DM, varieties of drugs with a different mechanism of action are used to maintain glycemic control [7] . Patients with T2DM are at risk of drug-related problems (DRP), which can happen at any step during the treatment process [8,9,10] and it affects the therapeutic outcome [3,11] .…”

Section: Introductionmentioning

confidence: 99%

Assessment of Drug-Related Problems among Type 2 Diabetic Patients on Follow up at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

Abdulmalik

Tadiwos

Legesse

2019

Preprint

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Objectives: To assess the drug-related problem among patients with type 2 diabetes at Hiwot Fana Specialized University Hospital Results: In this study, a total of 148 patient medication records were included. More than half, 83(57.4%) were men and the rest 65(42.6%) were women. The mean age of the study participants was 51.26 ± 7.08. Around one third (74.3%) of the participants had urban residency. A total of 127 drug-related problems were identified, of which dosage too low was the most common type of DRP encountered, 46(36.2%), followed by unnecessary drug therapy, 25(19.7%) and ineffective drug therapy, 25(19.7%). 95(64.2%) of the patients had at least one drug-related problem.Among patients with DRP, more than half of them, 59 (62.1%) had a single DRP. Out of the total participants, 85(57.4%) of them were taking one anti-diabetic medication and 63(42.6%) of them dual anti-diabetic medications. Only half of the patients have attained the desired FBG level. There was no patient who had experienced more than two types of drug-related problems at a time. Less than 10% of patients were taking five or more drugs at a time.

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“…Hence, timely and prompt diagnosis, life style modifications along with regular treatment would help to reduce the risk potentials and mortality risk. [18][19][20] The present study investigated the management of hypertension in patients with concurrent diabetes mellitus living in a rural setting. 12% 8%…”

Section: Discussionmentioning

confidence: 99%

A study on management of hypertension in patients with type 2 diabetes mellitus in tertiary care teaching rural hospital

Brahmbhatt¹,

Sattigeri²

2018

Int J Basic Clin Pharmacol

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Background: This study was aimed to analyze the drug utilization pattern in the management of hypertension in diabetic patients.Methods: A prospective, observational and non interventional study was conducted in 100 diabetic hypertensive patients admitted in medicine wards at Dhiraj Hospital. Patients who signed informed consent form were only included in the study. All the data were recorded from patients’ case files and analyzed.Results: Of enrolled 100 patients, 69 (69%) were male and 31 (31%) were female and maximum number of the patients (42%) were found in the age group of 51-60 years. Out of 100 admitted patients, 75% patients were treated with single antihypertensive agent, 20% were treated with combination of two antihypertensive agents while only 5% were administered more than two antihypertensive agents. As a single antihypertensive agent, most commonly prescribed was ACE inhibitors (32%), Calcium Channel Blockers (23%), Angiotensin Receptor Blockers (12%) and β1 blockers (8%).Conclusions: There was poor awareness among the patients regarding control of hypertension, regular follow up, medication adherence etc. However, two third of diabetic patients had achieved blood pressure target control and ACE inhibitor remained first choice of drug for hypertension in diabetes in this study.

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A prospective study on drug utilization pattern and rationality in treatment of type II diabetes mellitus: a population based analysis

Cited by 14 publications

References 16 publications

Prescription pattern of anti-diabetic drugs in a rural area of South Malabar region of Kerala, South India

Prescription pattern of anti-diabetic drugs in a rural area of South Malabar region of Kerala, South India

Assessment of Drug-Related Problems among Type 2 Diabetic Patients on Follow up at Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

A study on management of hypertension in patients with type 2 diabetes mellitus in tertiary care teaching rural hospital

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