A prospective study on physical performance of Chinese chronic obstructive pulmonary disease males with type 2 diabetes

Liu, Junhong; Song, Xiao; Zheng, Shuangshuang; Ding, Hui; Wang, Honggang; Sun, Xicai; Ren, Xiangfeng

doi:10.1097/md.0000000000027126

Cited by 2 publications

(1 citation statement)

References 30 publications

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“… 36 , 37 In contrast, hyper glycaemia can also cause a decline in lung function and physical performance. 38 For instance, in a 30-year follow-up study involving more than 27,000 non-smokers, low FEV 1 was found to precede diabetes and has a significant predictive effect on diabetes incidence. 39 Multiple shared risk factors and pathological changes play a vital role in their cooccurrence and interaction, including smoking, obesity, age, hypoxia, oxidative stress, inflammation, and so on.…”

Section: Copd and Endocrine Diseasesmentioning

confidence: 99%

Extrapulmonary Comorbidities Associated with Chronic Obstructive Pulmonary Disease: A Review

Xiang,

Luo

2024

COPD

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Most patients with chronic obstructive pulmonary disease (COPD) suffer from at least one additional, clinically relevant chronic disease. To a degree, the high global prevalence and mortality rate of COPD is closely related to its extrapulmonary effects. Moreover, the various of comorbidities of COPD and itself interact with each other, resulting in diverse clinical manifestations and individual differences, and thus further influencing the prognosis as well as healthcare burden of COPD patients. This is closely related to the common risk factors of chronic diseases (aging, smoking, inactivity, etc.). Additionally, some pathophysiological mechanisms caused by COPD, including the systemic inflammatory response, hypoxia, oxidative stress, and others, also have an impact on other systems. But comprehensive management and medical interventions have not yet been established. The clinicians should improve their knowledge and skills in diagnosing as well as treating the comorbidities of COPD, and then aim to develop more individualized, efficient diagnostic and therapeutic strategies for different patients to achieve greater clinical benefits. In this article, we will review the risk factors, mechanisms, and treatment strategies for extrapulmonary comorbidities in chronic obstructive pulmonary disease, including cardiovascular diseases, diabetes, anemia, osteoporosis, emotional disorders, and gastroesophageal reflux disease.

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Section: Copd and Endocrine Diseasesmentioning

confidence: 99%

Extrapulmonary Comorbidities Associated with Chronic Obstructive Pulmonary Disease: A Review

Xiang,

Luo

2024

COPD

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High-Resolution Computer Tomography Image Features of Lungs for Patients with Type 2 Diabetes under the Faster-Region Recurrent Convolutional Neural Network Algorithm

Tan

Han

2022

Computational and Mathematical Methods in Medicine

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The objective of this study was to adopt the high-resolution computed tomography (HRCT) technology based on the faster-region recurrent convolutional neural network (Faster-RCNN) algorithm to evaluate the lung infection in patients with type 2 diabetes, so as to analyze the application value of imaging features in the assessment of pulmonary disease in type 2 diabetes. In this study, 176 patients with type 2 diabetes were selected as the research objects, and they were divided into different groups based on gender, course of disease, age, glycosylated hemoglobin level (HbA1c), 2 h C peptide (2 h C-P) after meal, fasting C peptide (FC-P), and complications. The research objects were performed with HRCT scan, and the Faster-RCNN algorithm model was built to obtain the imaging features. The relationships between HRCT imaging features and 2 h C-P, FC-P, HbA1c, gender, course of disease, age, and complications were analyzed comprehensively. The results showed that there were no significant differences in HRCT scores between male and female patients, patients of various ages, and patients with different HbA1c contents ( P > 0.05 ). As the course of disease and complications increased, HRCT scores of patients increased obviously ( P < 0.05 ). The HRCT score decreased dramatically with the increase in the contents of 2 h C-P and FC-P after the meal ( P < 0.05 ). In addition, the results of the Spearman rank correlation analysis showed that the course of disease and complications were positively correlated with the HRCT scores, while the 2 h C-P and FC-P levels after meal were negatively correlated with the HRCT scores. The receiver operating curve (ROC) showed that the accuracy, specificity, and sensitivity of HRCT imaging based on Faster-RCNN algorithm were 90.12%, 90.43%, and 83.64%, respectively, in diagnosing lung infection of patients with type 2 diabetes. In summary, the HRCT imaging features based on the Faster-RCNN algorithm can provide effective reference information for the diagnosis and condition assessment of lung infection in patients with type 2 diabetes.

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A prospective study on physical performance of Chinese chronic obstructive pulmonary disease males with type 2 diabetes

Cited by 2 publications

References 30 publications

Extrapulmonary Comorbidities Associated with Chronic Obstructive Pulmonary Disease: A Review

Extrapulmonary Comorbidities Associated with Chronic Obstructive Pulmonary Disease: A Review

High-Resolution Computer Tomography Image Features of Lungs for Patients with Type 2 Diabetes under the Faster-Region Recurrent Convolutional Neural Network Algorithm

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