A Prospective Trial Using Mifepristone and Vaginal Misoprostol in Termination of Pregnancies up to 63 Days of Gestation

Kumar, Sumit; Patvekar, Meenal; Deshpande, Hemant

doi:10.1007/s13224-013-0407-1

Cited by 5 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Kumar S et al, found complete abortion by medical abortion in 95.6% of patients. 6 Similarly, Grossman D et al, found complete abortion rate by medical abortion in 93.8% of cases. 7 Silvestre L et al, and Nicholas CW Hill, studied different prostaglandin composition with mifepristone and found similar efficacy of different regimes.…”

Section: Discussionmentioning

confidence: 93%

Efficacy of combination of oral mifepristone and vaginal misoprostol in termination of pregnancy up to 63 days of gestation

Gupta

2019

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

Background: Unsafe and illegal abortions are one of the major problems in women health in India. Despite legal approval for medical termination of pregnancy in 1971, unsafe abortion still remains the third leading cause of maternal deaths in the country, contributes eight percent of such deaths annually. The objective of this study was to study efficacy of Mifepristone 200 mg orally followed 36-48 hours later by Misoprostol 800 microgms per vaginally in women undergoing medical termination of early pregnancy (up to 63 days of gestational age).Methods: The present study included 60 pregnant women requesting termination of pregnancy in the first trimester. Women who fulfilled the inclusion criteria were included in the study. Women without medical or surgical contraindications to Mifepristone and Misoprostol were included. Patients with previous caesarean sections were also included.Results: In our study 60 women were included, majority were in age group 20-29 years of age and majority of cases were primipara or multipara. The success rate in terms of complete abortion was 97%, 2% needed surgical evacuation and 1% lost to follow up. Side effects were nausea, vomiting, diarrhoea, abdominal cramps, pyrexia etc. The method proved to be safe, effective, cheap, non-invasive and has minimal or no complications.Conclusions: Medical termination of pregnancy with oral mifepristone and vaginal misoprostol is an effective method for first trimester abortion. The prerequisite for the method is patient counselling, patient participation and willingness for regular follow up and to report any complication. Hence this method comes out to be a safe alternative to surgical method which is invasive and costly.

show abstract

Section: Discussionmentioning

confidence: 93%

Efficacy of combination of oral mifepristone and vaginal misoprostol in termination of pregnancy up to 63 days of gestation

Gupta

2019

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

show abstract

“…Midlevel provision of medical and aspiration abortion has been shown to be feasible in India, and amendments to the law to approve midlevel provision of abortion care services are currently under consideration by the Ministry of Health and Family Welfare [ 12 , 13 ]. Medical abortion using mifepristone and misoprostol is approved in India up to 63 days of gestation, and has been shown to be safe, reliable and effective [ 14 ], but awareness and knowledge is generally low among women and physicians, and implementation has been slow, especially in the public sector [ 15 , 16 ].…”

Section: Introductionmentioning

confidence: 99%

Medical students are afraid to include abortion in their future practices: in-depth interviews in Maharastra, India

et al. 2016

View full text Add to dashboard Cite

Background: Unsafe abortions are estimated to cause eight per-cent of maternal mortality in India. Lack of providers, especially in rural areas, is one reason unsafe abortions take place despite decades of legal abortion. Education and training in reproductive health services has been shown to influence attitudes and increase chances that medical students will provide abortion care services in their future practice. To further explore previous findings about poor attitudes toward abortion among medical students in Maharastra, India, we conducted in-depth interviews with medical students in their final year of education. Method: We used a qualitative design conducting in-depth interviews with twenty-three medical students in Maharastra applying a topic guide. Data was organized using thematic analysis with an inductive approach. Results: The participants described a fear to provide abortion in their future practice. They lacked understanding of the law and confused the legal regulation of abortion with the law governing gender biased sex selection, and concluded that abortion is illegal in Maharastra. The interviewed medical students' attitudes were supported by their experiences and perceptions from the clinical setting as well as traditions and norms in society. Medical abortion using mifepristone and misoprostol was believed to be unsafe and prohibited in Maharastra. The students perceived that nurse-midwives were knowledgeable in Sexual and Reproductive Health and many found that they could be trained to perform abortions in the future.

show abstract

Systematic Review of the Effectiveness, Safety, and Acceptability of Mifepristone and Misoprostol for Medical Abortion in Low- and Middle-Income Countries

Ferguson

Scott

2020

Journal of Obstetrics and Gynaecology Canada

View full text Add to dashboard Cite

A Prospective Trial Using Mifepristone and Vaginal Misoprostol in Termination of Pregnancies up to 63 Days of Gestation

Cited by 5 publications

References 3 publications

Efficacy of combination of oral mifepristone and vaginal misoprostol in termination of pregnancy up to 63 days of gestation

Efficacy of combination of oral mifepristone and vaginal misoprostol in termination of pregnancy up to 63 days of gestation

Medical students are afraid to include abortion in their future practices: in-depth interviews in Maharastra, India

Systematic Review of the Effectiveness, Safety, and Acceptability of Mifepristone and Misoprostol for Medical Abortion in Low- and Middle-Income Countries

Contact Info

Product

Resources

About