A protocol for directly accessing geminal C-4 diarylated pyrazol-5(4H)-onesviatandem C–H aryne insertion and their inceptive neurobiological evaluation

Abstract

Geminal C-4 diarylation of substituted pyrazol-5(4H)-ones with in situ generated arynes as the aryl source has been achieved in one flask operation. All the newly accessed C4-gem-diarylated pyrazolone entities were...