A quantitative approach to optical resolution

The Dutch Resolution Variant of the Classical Resolution of Racemates by Formation of Diastereomeric Salts: Family Behaviour in Nucleation Inhibition

“…We prefer the use of Fogassy S-factors (2 yield de) to express the overall efficiencies. [7] Scanning of 2 a/2 c ratios revealed that the optimal concentration for nucleation inhibition was 6 mol % of 2 c (see Supporting Information).…”

Separation of the Mixtures of Chiral Compounds by Crystallization

“…Therefore it is advisable to use the parameter F characterizing the efficiency of the procedure (F=ee*Y). 18 This factor is actually the yield of enantiomeric excess separated. (Earlier this factor was marked with the letter S, but it could refer to the configuration even if it was marked by a different font.…”

Time dependent efficiency of optical resolution of aminooxiranes with O,O'-dibenzoyl-(R,R)-tartaric acid

“…There is no regular tendency in the change of yields during resolutions of 1 and a small increase in the yield could be observed during the resolutions of 2. Comparison of the resolution efficiencies (S) 5 of the 144 hours resolutions and those of repeated resolutions (last lines in Table 1 and 2, respectively) shows that long crystallization times resulted in higher efficiencies in both cases. Prolonged crystallization time is also advantageous from a practical point of view since repeated salt and mother liquor workup procedures can be avoided.…”