With the development of urban built-up areas, accurately extracting the urban built-up area and spatiotemporal pattern evolution trends could be valuable for understanding urban sprawl and human activities. Considering the coarse spatial resolution of nighttime light (NTL) data and the inaccurate regional boundary reflection on point of interest (POI) data, land surface temperature (LST) data were introduced. A composite index method (LJ–POI–LST) was proposed based on the positive relationship for extracting the boundary and reflecting the spatial-temporal evolution of urban built-up areas involving the NTL, POIs, and LST data from 1993 to 2018 in this paper. This paper yielded the following results: (1) There was a spatial-temporal pattern evolution from north-east to south-west with a primary quadrant orientation of IV, V, and VI in the Hefei urban area from 1993–2018. The medium-speed expansion rate, with an average value of 14.3 km2/a, was much faster than the population growth rate. The elasticity expansion coefficient of urbanization of 1.93 indicated the incongruous growth rate between the urban area and population, leading to an incoordinate and unreasonable development trend in Hefei City. (2) The detailed extraction accuracy for urban and rural junctions, urban forest parks, and other error-prone areas was improved, and the landscape connectivity and fragmentation were optimized according to the LJ–POI–LST composite index based on a high-resolution remote sensing validation image in the internal spatial structure. (3) Compared to the conventional NTL data and the LJ–POI index, the LJ–POI–LST composite index method displayed an extraction accuracy greater than 85%, with a similar statistical and landscape pattern index result. This paper provides a suitable method for the positive relationship among these LST, NTL, and POI data for accurately extracting the boundary and reflecting the spatial-temporal evolution of urban built-up areas by the fusion data.