Quasi-zero stiffness is usually abbreviated as QZS. This kind of QZS isolator has a negative stiffness mechanism, which is usually a spring mechanism (NSSM), thus possessing excellent isolation performance. However, it is prone to instability under low-frequency and large amplitude excitation. In response to this situation, a novel type of cam and roller spring mechanism (CRSM) is designed. This mechanism is composed of an arc-shaped groove, a rolling element, a spring, and a sliding pair. Use the combination of CRSM and NSSM to improve the stability of QZS isolators and prevent instability. Under two typical excitations, simulation tests in SIMULINK are conducted to analyze the vibration attenuation performance of the improved isolator and the role of CRSM in improving stability. The conclusion is that CRSM can greatly improve stability without reducing vibration damping performance.