Most Chest X-Rays (CXRs) are used to spot the existence of chest diseases by radiologists worldwide. Examining multiple X-rays at the busiest medical facility may result in time and financial loss. Furthermore, in the detection of the disease, expert abilities and attention are needed. CXRs are usually used for the detection of heart and lung region anomalies. In this research, multi-level Deep Learning for CXRs ailment detection has been used to identify solutions to these issues. Spotting these anomalies with high precision automatically will significantly improve the processes of realistic diagnosis. However, the absence of efficient, public databases and benchmark analyses makes it hard to match the appropriate diagnosis techniques and define them. The publicly accessible VINBigData datasets have been used to address these difficulties and researched the output of established multi-level Deep Learning architectures on various abnormalities. A high accuracy in CXRs abnormality detection on this dataset has been achieved. The focus of this research is to develop a multi-level Deep Learning approach for Localization and Classification of thoracic abnormalities from chest radiograph. The proposed technique automatically localizes and categorizes fourteen types of thoracic abnormalities from chest radiographs. The used dataset consists of 18,000 scans that have been annotated by experienced radiologists. The YoloV5 model has been trained with fifteen thousand independently labeled images and evaluated on a test set of three thousand images. These annotations were collected via VinBigData's web-based platform, VinLab. Image preprocessing techniques are utilized for noise removal, image sequences normalization, and contrast enhancement. Finally, Deep Ensemble approaches are used for feature extraction and classification of thoracic abnormalities from chest radiograph.