2022
DOI: 10.1055/s-0042-1742609
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A Radiologist's Perspective on Treatment-Related Pseudoprogression: Clues and Hues

Abstract: Pseudoprogression refers to the initial apparent increase in tumor burden observed on imaging after cancer therapy, with subsequent delayed response to the same treatment, thus giving a false initial appearance of disease progression. It is essential to differentiate pseudoprogression from true progression to prevent the patients from getting deprived of the benefits of their ongoing cancer therapy owing to their early withdrawal. It also affects their recruitment for clinical trials. Pseudoprogression, albeit… Show more

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Cited by 5 publications
(2 citation statements)
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“…Imaging response assessment of extracerebral metastatic disease for those on systemic therapy should be performed using the latest version of Response Evaluation Criteria in Solid Tumors (RECIST 1.1) after chemotherapy and immune RECIST (iRECIST) after immunotherapy [100][101][102][103][104]. For the evaluation of the response of brain metastasis after chemotherapy, response assessment in neuro-oncology brain metastases (RANO BM) is used [101,105].…”
Section: Follow-upmentioning
confidence: 99%
“…Imaging response assessment of extracerebral metastatic disease for those on systemic therapy should be performed using the latest version of Response Evaluation Criteria in Solid Tumors (RECIST 1.1) after chemotherapy and immune RECIST (iRECIST) after immunotherapy [100][101][102][103][104]. For the evaluation of the response of brain metastasis after chemotherapy, response assessment in neuro-oncology brain metastases (RANO BM) is used [101,105].…”
Section: Follow-upmentioning
confidence: 99%
“…38 Im-mune-modified Response Evaluation Criteria in Solid Tumors (iRECIST) is used for assessing response in advanced EC receiving immunotherapy to take into account the phenomenon of pseudoprogression. 39,40 ►Fig. 5 (A and B) shows pre-treatment and postradiotherapy response on PET/CT.…”
Section: D) Response Assessmentmentioning
confidence: 99%