A randomised controlled trial comparing the use of omega-3 polyunsaturated fatty acid supplements versus very low calorie dietary restriction in obese Malaysian patients awaiting bariatric surgery

Abidin, Zainal Adwin Zainal; Kosai, Nik Ritza; Taher, Mustafa Mohd; Ghoneim, Iman; Shuhaili, Mohd Aznan; Yaacob, Nur Yasmin; Rajan, Reynu

doi:10.21037/ales.2017.06.12

Cited by 6 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Seventeen of the 18 studies on diet programmes included preoperative weight loss as an outcome, 15 of these were significant in either weight loss in kilograms (kg), percentage excess weight loss, percentage total weight loss or BMI postinterventional 5,13–15,18–28 . Other secondary outcomes of this study showed that the intervention group had significantly fewer 30‐day postoperative complications and less postoperative pain 13,20 .…”

Section: Resultsmentioning

confidence: 83%

“…Of the 33 articles (89%) that included preoperative weight loss as an outcome, 21 found a significant effect (64%) 5,13–15,18–28,30,40,43,44,46,47 . The highest percentage of significance in preoperative weight loss was found in the articles describing a combination of interventions, four authors investigated preoperative weight loss and used a combined intervention, and all of them were significant.…”

Section: Discussionmentioning

confidence: 99%

“…[12][13][14][15][16] Seventeen of the 18 studies on diet programmes included preoperative weight loss as an outcome, 15 of these were significant in either weight loss in kilograms (kg), percentage excess weight loss, percentage total weight loss or BMI postinterventional. 5,[13][14][15][18][19][20][21][22][23][24][25][26][27][28] Other secondary outcomes of this study showed that the intervention group had significantly fewer 30-day postoperative complications and less postoperative pain. 13,20 The intervention group had significantly reduced collagen I expression, 14 improved lipid profile, 15 higher urinary ketones, 17 lower blood glucose, 19,24 reduced liver volume, 16,[25][26][27] and larger preoperative bleeding 27 postinterventional.…”

Section: Dietmentioning

confidence: 98%

“…34,37 The time limit was set on the last decade, even though interventions could be the same for older studies, within the altering bariatric health care pathways its effect could be outdated. Also, there was a difference in comparing results across studies; some investigators did not utilize a control group, 5,25,26 others compared the intervention with usual care 12,[15][16][17][18][19][20][21][22][23][24][28][29][30][31][33][34][35][40][41][42][43][44][45] and some compared the intervention with a control group not receiving an intervention. 13,14,27,32,[36][37][38][39]46,47 This limitation makes it hard to compare outcomes across studies, which further supports the idea of Swierz et al; to produce a "core outcome set" for clinical trials in bariatric surgery.…”

Section: Limitationsmentioning

confidence: 99%

See 3 more Smart Citations

A broad focus on additional programmes prior to bariatric surgery: A systematic review

2022

View full text Add to dashboard Cite

Additional preoperative programmes may be beneficial for candidates who seek bariatric surgery, but there is no consensus on the optimal preparation. This systematic review aimed to summarize the effects of a preoperative programme on weight loss. A literature search was performed for Embase, Cinahl, PubMed and Cochrane Library.Studies on preoperative exercise, behaviour and/or diet programmes administered in adult patients in a bariatric trajectory measuring weight loss were included. Initial results yielded 2148 titles, 70 of which were thoroughly analysed and 37 articles were included, comprising 10 333 patients. Eleven out of 37 studies included postoperative weight loss as an outcome in interventions focused on diet (n = 5), behaviour (n = 2), exercise (n = 2) and a combination of interventions (n = 2). Only one study (9%) which administered exercise as a preoperative programme showed a significant effect on postoperative weight loss. In total, 33 studies included preoperative weight loss as an outcome, which was significant in 64% of the cases. It is difficult to draw conclusions from the investigated data as it was extremely heterogeneous concerning the intensity, duration and administration of a programme. Nevertheless, it seems that a preoperative weight loss programme seems beneficial in terms of preoperative weight loss, postoperative physical activity and improved mental health postinterventional. The use of a core outcome set is recommended for future studies.

show abstract

Section: Resultsmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%

Section: Dietmentioning

confidence: 98%

Section: Limitationsmentioning

confidence: 99%

See 2 more Smart Citations

A broad focus on additional programmes prior to bariatric surgery: A systematic review

2022

View full text Add to dashboard Cite

show abstract

“…The combined effects of a low-carbohydrate, high-protein diet plus omega-3 PUFA supplementation is not fully understood. In particular, Omega-3 polyunsaturated fatty acids (PUFAs) have also been shown to reduce hepatic steatosis and reduce the effects of visceral adipose tissue by influencing lipid metabolism and insulin sensitivity [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects

et al. 2021

View full text Add to dashboard Cite

Purpose This study aims to evaluate the effects of a VLCKD combined with omega-3 supplementation (VLCKD diet only lasted for some weeks, and it was followed by a non-ketogenic LCD for the rest of the study period) on body composition, visceral fat, satiety hormones, inflammatory and metabolic markers. Methods It has been performed a pilot open label study lasted 90 days, in a cohort of 12 women with class I obesity aged 18 to 65 years. Data on body composition (evaluated by Dual X-Ray Absorptiometry—DXA), visceral fat, satiety hormones, inflammatory and metabolic markers were recorded. Results This study showed a body weight reduction mean difference over time of −13.7 kg and the waist circumference mean difference decrease of −13.3 cm. Also, the fat mass (FM) decreased—9.1 kg and visceral adipose tissue (VAT)—0.41 kg. No effects on fat-free mass (FFM) have been reported. Improvements were observed in the satiety hormones, with increased ghrelin and decreased leptin, and also in the metabolic profiles. Conclusions A VLCKD combined with omega-3 supplementation appears to be an effective strategy for promoting an high loss of FM with preservation of FFM in patients with class I obesity.

show abstract

Low-calorie diets are effective for weight loss in patients undergoing benign upper gastrointestinal surgery: a systematic review and meta-analysis

Chowdhury,

Hasnan,

Ullah

et al. 2024

Surg Endosc

View full text Add to dashboard Cite

Background Obesity may increase surgical complexity in patients undergoing abdominal surgery by limiting visualization and increasing the risk of peri-operative complications. A preoperative reduction in weight and liver volume may improve surgical outcomes. The aim of our study was to evaluate the efficacy of a low-calorie diet (LCD) versus a very low-calorie diet (VLCD) in reducing weight and liver volume prior to laparoscopic surgery. Methods A systematic search was conducted using the following inclusion criteria: obese patients undergoing preoperative weight loss using a VLCD or LCD, evaluation of liver volume reduction, and the use of an imaging modality before and after the diet. Results A total of 814 patients from 21 different studies were included in this systematic review and meta-analysis, with 544 female patients (66.8%) and a mean age range between 24 and 54 years old. There was a total mean weight loss of 6.42% and mean liver volume reduction of 16.7%. Meta-analysis demonstrated that a preoperative diet (LCD or VLCD) significantly reduced weight [SMD = − 0.68; 95% CI (− 0.93, − 0.42), I2 = 82%, p ≤ 0.01] and liver volume [SMD = − 2.03; 95% CI (− 4.00, − 0.06), I2 = 94%, p ≤ 0.01]. When assessed individually, a VLCD led to significant weight reduction [SMD = − 0.79; CI (− 1.24; − 0.34), p ≤ 0.01, I2 = 90%], as did an LCD [SMD = − 0.60; CI (− 0.90; − 0.29), p ≤ 0.01, I2 = 68%). Similarly, there was a significant reduction in liver volume following a VLCD [SMD = − 1.40; CI (− 2.77, − 0.03), p ≤ 0.01, I2 = 96%], and an LCD [SMD = − 2.66; CI (− 6.13, 0.81), p ≤ 0.01, I2 = 93%]. However, there was no significant difference between the two regimens. Conclusions Preoperative restrictive calorie diets are effective in reducing weight and liver volume prior to laparoscopic surgery. Whilst a VLCD was better than an LCD at reducing both weight and liver volume, the difference was not significant. Graphical abstract

show abstract

A randomised controlled trial comparing the use of omega-3 polyunsaturated fatty acid supplements versus very low calorie dietary restriction in obese Malaysian patients awaiting bariatric surgery

Cited by 6 publications

References 0 publications

A broad focus on additional programmes prior to bariatric surgery: A systematic review

A broad focus on additional programmes prior to bariatric surgery: A systematic review

Effect of very low-calorie ketogenic diet in combination with omega-3 on inflammation, satiety hormones, body composition, and metabolic markers. A pilot study in class I obese subjects

Low-calorie diets are effective for weight loss in patients undergoing benign upper gastrointestinal surgery: a systematic review and meta-analysis

Contact Info

Product

Resources

About