A randomised trial of post-discharge enteral feeding following surgical resection of an upper gastrointestinal malignancy

Froghi, Farid; Sanders, Grant; Berrisford, Richard; Wheatley, Tim; Peyser, P; Rahamim, J; Lewis, Stephen J.

doi:10.1016/j.clnu.2016.10.022

Cited by 20 publications

(21 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is especially important in elderly patients 132 . Maintenance of enteral nutrition in home care (with home-based nutritional therapy) may contribute to increase nutritional intake after major operations 133 and prevent post-operative nutritional deterioration 134,135 .…”

Section: Howmentioning

confidence: 99%

ACERTO guidelines of perioperative nutritional interventions in elective general surgery

De-Aguilar-Nascimento

Salomão

Waitzberg

et al. 2017

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

Objective: to present recommendations based on the ACERTO Project (Acceleration of Total Post-Operative Recovery) and supported by evidence related to perioperative nutritional care in General Surgery elective procedures. Methods: review of relevant literature from 2006 to 2016, based on a search conducted in the main databases, with the purpose of answering guiding questions previously formulated by specialists, within each theme of this guideline. We preferably used randomized controlled trials, systematic reviews and meta-analyzes but also selected some cohort studies. We contextualized each recommendation-guiding question to determine the quality of the evidence and the strength of this recommendation (GRADE). This material was sent to authors using an open online questionnaire. After receiving the answers, we formalized the consensus for each recommendation of this guideline. Results: the level of evidence and the degree of recommendation for each item is presented in text form, followed by a summary of the evidence found. Conclusion: this guideline reflects the recommendations of the group of specialists of the Brazilian College of Surgeons, the Brazilian Society of Parenteral and Enteral Nutrition and the ACERTO Project for nutritional interventions in the perioperative period of Elective General Surgery. The prescription of these recommendations can accelerate the postoperative recovery of patients submitted to elective general surgery, with decrease in morbidity, length of stay and rehospitalization, and consequently, of costs.

show abstract

Section: Howmentioning

confidence: 99%

ACERTO guidelines of perioperative nutritional interventions in elective general surgery

De-Aguilar-Nascimento

Salomão

Waitzberg

et al. 2017

Rev. Col. Bras. Cir.

View full text Add to dashboard Cite

show abstract

“…2 Although we have no information on the use of postoperative enteral feeding and skeletal muscle index in this setting, enteral feeding has not demonstrated improvement in terms of postoperative weight loss. 3 Nagata et al 4 also studied postoperative skeletal muscle mass after esophagectomy and found that reduced skeletal muscle in the psoas muscle 6 months after esophagectomy did not correlate with preoperative nutrition status or neoadjuvant therapy. Their series showed no association with cancer recurrence, although the patients with presarcopenia at the 6-month mark did have more pneumonia and a doubling of 12-month mortality (24.1% vs 11.7%; p = 0.11).…”

mentioning

confidence: 99%

Prognostic Significance of Skeletal Muscle Loss During Early Postoperative Period in Elderly Patients with Esophageal Cancer

et al. 2019

View full text Add to dashboard Cite

In this issue of Annals of Surgical Oncology, Takahashi et al. 1 report that skeletal muscle reduction in the highest tertile of their patient series was associated with worse cancer-free and overall survival after an oncologic esophagectomy. The patients were 65 years of age or older, had no cancer recurrence at 4 months, and had undergone R0 resections.The skeletal muscle index (SMI) analysis remained significant in the multivariate analysis for recurrence-free and overall survival. In fact, SMI loss in the highest tertile of patients had a hazard ratio (HR) of 5.405 for death (p \ 0.001; 95% confidence interval [CI], 3.514-8.314) and showed similar findings for recurrence-free survival. The patients with the highest tertile of skeletal muscle loss had more node-positive pathology at the time of resection, suggesting that the presence of microscopic disease may have correlated with the loss of skeletal muscle.Pre-therapeutic sarcopenia in esophageal cancers is highly prevalent as well as significantly and independently associated with postoperative complications, chemotherapy-induced toxicity, and poor survival in cancer patients, as shown in a recent systematic review. 2 Although we have no information on the use of postoperative enteral feeding and skeletal muscle index in this setting, enteral feeding has not demonstrated improvement in terms of postoperative weight loss. 3

show abstract

“…Most prior studies have focused on the benefit of home enteral nutrition and home parenteral nutrition (HPN) in EC patients undergoing esophagectomy (25)(26)(27). To our acknowledge, this study was the first RCT to compare a planned program of oral nutritional supplement to usual care in EC patients.…”

Section: Discussionmentioning

confidence: 99%

“…However, the mean difference of BWL between the two groups was 1.89 and 1.97 kg, respectively, at 3 and 6 months. The study by Froghi et al (27), which investigated the value of 6 weeks enteral feeding following resection of an upper gastrointestinal malignancy, showed that the mean differences of BWL were 1.5 and 1.3 kg between the intervention group and control group at 12 and 24 weeks, respectively. Although these differences were obvious, there were not statistically significant.…”

Section: Discussionmentioning

confidence: 99%

A randomized controlled trial of oral nutritional supplementation versus standard diet following McKeown minimally invasive esophagectomy in patients with esophageal malignancy: a pilot study

Xie¹,

Chen²,

Xu³

et al. 2021

Ann Transl Med

View full text Add to dashboard Cite

A randomised trial of post-discharge enteral feeding following surgical resection of an upper gastrointestinal malignancy

Cited by 20 publications

References 13 publications

ACERTO guidelines of perioperative nutritional interventions in elective general surgery

ACERTO guidelines of perioperative nutritional interventions in elective general surgery

Prognostic Significance of Skeletal Muscle Loss During Early Postoperative Period in Elderly Patients with Esophageal Cancer

A randomized controlled trial of oral nutritional supplementation versus standard diet following McKeown minimally invasive esophagectomy in patients with esophageal malignancy: a pilot study

Contact Info

Product

Resources

About