A randomized anesthethic potency comparison between ropivacaine and bupivacaine on the perioperative regional anesthesia in lower third molar surgery

Clinical efficacy of 0.75% ropivacaine vs. 2% lignocaine hydrochloride with adrenaline (1:80,000) in patients undergoing removal of bilateral maxillary third molars: a randomized controlled trial

“…After its commercial release, ropivacaine has been extensively used for perioperative pain relief in the medical field, with consistently better outcomes than other local anesthetic agents [ 4 ]. Its use in the dental discipline has expanded to studies on periodontic procedures to evaluate its anesthetic efficacy [ 11 ], topical anesthesia of the oral mucosa [ 12 ], simple extraction procedures [ 3 13 14 ], lower third molar surgeries[ 1 4 5 15 16 17 18 19 ], surgical removal of the upper third molars[ 20 ], surgical removal of chronic periapical lesions [ 21 ], oral aphthosis [ 22 ], mandibular osteotomy [ 23 ], and postoperative pain control after elective cleft palate repair in children [ 24 ].…”

The Assessment of Prolonged Inferior Alveolar Nerve Blockade for Postoperative Analgesia in Mandibular Third Molar Surgery by a Perineural Addition of Dexamethasone to 0.5% Ropivacaine: A Randomized Comparison Study

“…The inclusion criteria included a randomly selected asymptomatic cohort with radiologically classified horizontally impacted third molars, according to the Winter' s scale of mandibular third molar impaction [11], and without pain, trismus, swelling, infection, pericoronitis, corticosteroid medications and antibiotic therapy 14 days before surgery.…”

“…CONSORT (Consolidate Standards of Reporting Trials) principles were applied in this study, and the selection of all the included arbitrarily selected patients was performed by using the sealed envelope technique, previously used in similar studies [11]. Out-patients of both sexes, in the age range of 17 to 50, with physical status Grade I (ASA I), were selected for this study, according to the American Society of Anesthesiologists.…”

“…Ropivacaine is also used as a long-lasting amid anesthetic in various types of oral surgery practice but not only for impacted third molar surgery [10]. Some studies show that the patients could be relieved of the first postoperative pain to a certain extent when compared to those who received plain 0.75% ropivacaine and to 0.5% bupivacaine, but analgesics and anti-inflammatories are almost mandatory during this time [11]. Considering the possible toxic reaction of cardiovascular and neural tissue, ropivacaine has been shown to be a safer anesthetic than bupivacaine [12,13].…”

“…Therefore, pain management in clinical surgical praxis constantly exhibits the need for a pain-free early postoperative period of the surgical patient for as long as possible, achieved in the safest, simplest and most practical clinical manner. It is not surprising that, for that purpose, there is evidence of the use of long-acting local anesthetics for achieving longer-lasting intraoperative local anesthesia in oral surgery [10,11] and controlling postoperative pain, thus increasing the early postoperative pain-free interval and minimizing the intake of postoperative analgesic [1,17]. In addition, adding different adjuvants to local anesthetics for the purpose of prolonging the effects of local anesthesia for clinically relevant postoperative analgesia is described in surgical practice [18,19].…”