A Randomized, Clinical Trial to Evaluate the Impact of Regular Physical Activity on the Quality of Life, Body Morphology and Metabolic Parameters of Patients With AIDS in Salvador, Brazil

Ogalha, Cecília Fontes Schmidt; Luz, Estela; Sampaio, Ethiane; Souza, Rodrigo Martins de; Zarife, André Sant'Anna; Neto, Mansueto Gomes; Netto, Eduardo Martins; Brites, Carlos

doi:10.1097/qai.0b013e31821e9bca

Cited by 62 publications

(160 citation statements)

References 15 publications

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“…Exercise has been shown to reduce WC in HIV-patients (35); therefore, there may be a role for exercise as a potential strategy to improve nutritional status and, consequently, QoL (31,35). In contrast to the limited available evidence on AMA and QoL suggesting a positive relationship between the two (36), an inverse relationship was found in the present study, where the lowest QoL scores were observed in subjects with ≥ adequate AMA measurements (though similar scores were observed for lower than adequate and adequate categories).…”

Section: Discussionmentioning

confidence: 99%

Nutritional Status and Quality of Life in HIV-infected patients

2017

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Key words:HIV. Nutritional status. Quality of life. Palabras clave:VIH. Estado nutricional. Calidad de vida. ResumenIntroducción: el estado nutricional y la evolución del virus de inmunodefi ciencia humana (VIH) están interconectados. A pesar de que algunos estudios hayan visto el impacto del estado nutricional en la calidad de vida (CdV) en pacientes con enfermedades crónicas, pocos han estudiado sus efectos en pacientes infectados de VIH. Objetivo: investigar la relación entre el estado nutricional y la CdV en adultos recientemente diagnosticados de VIH. Métodos: cumplieron los criterios de inclusión los individuos diagnosticados de VIH en los 14 meses previos a una visita al hospital central de Lisboa. El estado nutricional fue evaluado por antropometría, análisis de la composición del cuerpo, y dieta, mientras que la CdV fue evaluada usando el cuestionario WHOQOL-HIV-BREF. También fueron considerados los datos sociodemográfi cos y clínicos. Resultados: fueron seleccionados 51 individuos, la mayoría de sexo masculino, caucásicos, empleados, solteros y en tratamiento antirretroviral de gran actividad (TARGA). Varias características sociodemográfi cas, como el nivel de educación, la edad, el sexo y el estado de salud actual, fueron importantes indicadores del nivel de CdV (p < 0,05). Se observaron niveles de CdV más bajos en individuos con dietas inadecuadas, pérdida de peso comprobada y elevado perímetro de cintura en análisis bivariado (p < 0,05). Las mismas variantes infl uenciaron negativamente la CdV tras haber ajustado los factores de confusión en análisis multivariado (p < 0,05). Conclusión: varios aspectos del estado nutricional infl uyeron en las variaciones observadas en la CdV, lo que sugiere que una intervención a nivel nutricional podría mejorar potencialmente la calidad de vida en esta población. AbstractIntroduction: Nutritional status and the progression of the human immunodefi ciency virus (HIV) are interlinked; though some studies have looked at the impact nutritional status has on quality of life (QoL) in patients with chronic diseases, few have studied this in HIV-infected individuals. Objective: To investigate the relationship between nutritional status and QoL in adults with a recent HIV diagnosis. Methods: Individuals with an HIV diagnosis performed in the fourteen months prior to a medical visit to one of Lisbon's central hospitals were eligible. Nutritional status was assessed by anthropometry, body composition analysis, and dietary intake. QoL was assessed using the WHOQOL-HIV-BREF questionnaire. Sociodemographic and clinical data were also considered. Results: Fifty-one subjects were eligible for enrolment; the majority were male, Caucasian, employed, single, and under highly active antiretroviral therapy (HAART). Lower QoL scores were observed in subjects with inadequate energy intakes, reported weight loss, and a high waist circumference in bivariate analysis (p < 0.05); the same variables infl uenced QoL negatively after adjusting for confounders in multivariate analysis (p < 0.05)...

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Section: Discussionmentioning

confidence: 99%

Nutritional Status and Quality of Life in HIV-infected patients

2017

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“…Moreover, it has the benefi t of being inexpensive and easy to use and is recommended by the World Health Organization 17,50 . St udies have demonstrated the benefi cial effects of regular physical activity, including improved metabolic profi le 50 , body composition, and quality of life 51,52 , in HIV-infected individuals.…”

Section: Tien and Grunfeldmentioning

confidence: 99%

Prevalence and factors associated with lipodystrophy in AIDS patients

Justina

Luiz

Silva

et al. 2014

Rev. Soc. Bras. Med. Trop.

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“…A recently published randomized clinical trial evaluated the impact of regular physical activity on the quality of life, body morphology, and metabolic parameters in patients with AIDS, although the issue of chronic inflammation and immune activation was not investigated. 58 In this study, patients were randomly assigned to receive a 1-h supervised gym class three times a week plus monthly nutritional counseling (intervention group) or to participate in monthly workshops to discuss the importance of physical activity and receive nutritional counseling (control group). After intervention, the exercise group showed a decrease in fat mass, resting heart rate, waist circumference, and serum glucose, as well as an increase in muscle mass, CD4…”

Section: -57mentioning

confidence: 99%