A randomized controlled clinical trial on efficacy of photodynamic therapy as an adjunct to nonsurgical treatment of chronic periodontitis

Malgikar, Suryakanth; Reddy, Srikanth; Babu, Palaparthy Raja; S, Sagar; Kumar, Prabin; Reddy, G Jagdish

doi:10.4103/0976-2868.170562

Cited by 5 publications

(4 citation statements)

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“…The table shows the risk of bias of each study included in the review (a green symbol was assigned where the information was complete and accurate; a yellow symbol was allocated where information was missing; a red symbol was assigned where the information did not meet the requirements). [28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. The table shows the risk of bias of each study included in the review (a green symbol was assigned where the information was complete and accurate; a yellow symbol was allocated where information was missing; a red symbol was assigned where the information did not meet the requirements).…”

Section: Incomplete Registrationmentioning

confidence: 99%

“…RCTs included (laser)[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47].…”

mentioning

confidence: 99%

“…of bias of articles (laser)[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. The table shows the risk of bias of each study included Appl.…”

mentioning

confidence: 99%

“…Risk of bias of articles (laser)[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. The table shows the risk of bias of each study included in the review (a green symbol was assigned where the information was complete and accurate; a yellow symbol was allocated where information was missing; a red symbol was assigned where the information did not meet the requirements).…”

mentioning

confidence: 99%

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Effectiveness of Ultrasonic and Manual Instrumentation in Nonsurgical Periodontal Therapy: Are Additional Therapies More Effective? A Systematic Review

Sabatini,

Maiorani,

Bassignani

et al. 2024

Applied Sciences

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Nonsurgical periodontal therapy aims to remove supragingival and subgingival biofilm to restore periodontal health. This systematic review aims to assess the clinical effectiveness of manual and/or ultrasonic instruments and to determine whether other therapies can improve periodontal clinical outcomes. Case-control, cross-sectional and cohort studies and clinical trials of patients undergoing nonsurgical periodontal therapy with ultrasonic and/or manual instruments (and any adjunctive therapies, such as glycine, erythritol, ozone, laser and glycine) from 2013 to 2023 were analyzed using Pub-med/MEDLINE, Scopus and Google Scholar. To assess the risk of bias in this review, blinding, randomization, allocation concealment, outcome data and outcome recording were assessed. No differences between treatments were found; all methods, including manual and ultrasound, were helpful in improving clinical parameters (primary outcome). Although the results were mixed, adjunctive therapies seemed to be helpful in the treatment of periodontal disease. The results of this systematic review are consistent with the previous scientific literature and have shown that both manual and ultrasonic instruments are effective in nonsurgical periodontal therapy. This review could not show how complementary therapies could further improve nonsurgical periodontal therapy. For future research, it would be good to standardize the sample with regard to the degree and stage of periodontal disease and to evaluate the risks and benefits of the instruments (manual and ultrasonic scalers).

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Section: Incomplete Registrationmentioning

confidence: 99%

“…RCTs included (laser)[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47].…”

mentioning

confidence: 99%

“…of bias of articles (laser)[28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47]. The table shows the risk of bias of each study included Appl.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

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Effectiveness of Ultrasonic and Manual Instrumentation in Nonsurgical Periodontal Therapy: Are Additional Therapies More Effective? A Systematic Review

Sabatini,

Maiorani,

Bassignani

et al. 2024

Applied Sciences

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Clinical efficacy of photodynamic therapy adjunctive to scaling and root planing in the treatment of chronic periodontitis: A systematic review and meta-analysis

Xue

Tang

Bai

et al. 2017

Photodiagnosis and Photodynamic Therapy

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A review of antimicrobial photodynamic therapy (aPDT) in periodontitis

Condor

Culcitchi

Baru³

et al. 2020

BALNEO

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Introduction:Periodontitis is an inflammatory disease caused by a multitude of pathogens, that eventually affects the entirety of all periodontal tissues and may lead to tooth mobility or even tooth loss. The destruction of said tissues occurs via 2 pathways: a direct pathway (defense mechanisms belonging to the pathogens) and an indirect pathway (the host’s immune system). Therapy is complex and requires strict follow-ups in order to prevent relapse. Aim: Our objective was to determine whether or not aPDT can be considered to be an effective adjunctive approach to the current standard initial treatment method when dealing with periodontitis (scaling/root planing). Methods: We performed an electronical search of the PubMed and ScienceDirect data bases starting from January 2014 and up to May 2019. Eligibility criteria included English-language systematic reviews and randomized clinical trials which evaluated the efficiency of aPDT, and that had been carried out on human subjects with permanent dentition. We excluded studies and reviews that were focused on the microbiology and/or immunology in photodynamic therapy and also those that used other LASER treatment modalities than aPDT. Results: Current literature displays many opinions regarding periodontal therapy with adjunctive aPDT, but it seems to be mainly regarded as a safe, effective and easy-to-use approach. Conclusion: aPDT seems to be efficient in the treatment of periodontitis when carried out additionally to classical scaling/root planing. Residual pockets seem to respond well to aPDT, as opposed to subsequent debridement flap elevation and its consequences on hard and soft tissues. However, further studies with a stricter treatment protocol and subsequent follow-ups are required in order to obtain a firmer conclusion. Key words: periodontitis LASER, periodontitis aPDT, periodontitis photodynamic therapy,

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A randomized controlled clinical trial on efficacy of photodynamic therapy as an adjunct to nonsurgical treatment of chronic periodontitis

Cited by 5 publications

References 0 publications

Effectiveness of Ultrasonic and Manual Instrumentation in Nonsurgical Periodontal Therapy: Are Additional Therapies More Effective? A Systematic Review

Effectiveness of Ultrasonic and Manual Instrumentation in Nonsurgical Periodontal Therapy: Are Additional Therapies More Effective? A Systematic Review

Clinical efficacy of photodynamic therapy adjunctive to scaling and root planing in the treatment of chronic periodontitis: A systematic review and meta-analysis

A review of antimicrobial photodynamic therapy (aPDT) in periodontitis

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