The aim of this study was to determine the effect of real-time videos with smart glasses on the performance of cardiopulmonary resuscitation performed by nursing students. In this randomized controlled pilot study, the students were randomly assigned to the smart glass group (n = 12) or control group (n = 8). Each student's cardiopulmonary resuscitation performance was evaluated by determining sequential steps in the American Heart Association algorithm they applied and the accuracy and time of each step. A higher number of participants correctly checked response breathing, requested a defibrillator, activated the emergency response team, and provided appropriate chest compressions and breaths in the smart glass group than the control group. There were significant differences between groups. Furthermore, more participants significantly corrected chest compression rate and depth and hand location, used a defibrillator, and sustained cardiopulmonary resuscitation until the emergency response team arrived in the smart glass group than in the control group. Additionally, a significantly shorter time was observed in the smart glass group than in the control group in all variables except time to activate the emergency response team (P < .05). Remote expert assistance with smart glass technology during cardiopulmonary resuscitation is promising. Smart glass led to a significantly better ABC (airway, breathing, circulation) approach, chest compression depth and rate, and hand position. Furthermore, remote expert assistance with smart glass has the potential to improve overall resuscitation performance because it enabled students to initiate resuscitation, use a defibrillator, and defibrillate patients earlier. Nurses may benefit from smart glass technology in real life to provide effective cardiopulmonary resuscitation.