A randomized controlled trial evaluating Mindfulness-Based Stress Reduction (MBSR) for the treatment of palpitations: A pilot study

Owens, Justine E.; Schorling, John B.; Plews-Ogan, Margaret; Goodman, Matthew; Moorman, Randall; Zaklin, Ryan; Dent, John

doi:10.1016/j.ijcard.2016.08.183

Cited by 18 publications

(22 citation statements)

References 10 publications

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“…Out of 10 included studies [36,37,40,41,42,43,50,51,52,53] that in total comprised 607 participants, 9 studies were RCTs [37,40,41,42,43,50,51,52,53], while no randomization was used for allocating patients into intervention and control groups in the study by Lee et al [36]. Trials were mainly conducted in the USA and Canada [40,42,43,50,51,53], with fewer studies coming from Europe [41,52], New Zealand [37], and South Korea [36]. Furthermore, 8 out of 10 studies were conducted in out-patient clinics [36,37,42,43,50,51,52,53], with community-dwelling individuals being recruited in two other studies [40,41].…”

Section: Resultsmentioning

confidence: 99%

“…Trials were mainly conducted in the USA and Canada [40,42,43,50,51,53], with fewer studies coming from Europe [41,52], New Zealand [37], and South Korea [36]. Furthermore, 8 out of 10 studies were conducted in out-patient clinics [36,37,42,43,50,51,52,53], with community-dwelling individuals being recruited in two other studies [40,41]. Only one study focused on healthy individuals [40], while other studies recruited patients with social anxiety [50], moderate depression and anxiety [52], generalized anxiety disorder (GAD) [51], stress-related complaints [41], breast cancer [36,42], rheumatoid arthritis [37], heart palpitations [43], and post-menopausal BMI > 30 [53].…”

Section: Resultsmentioning

confidence: 99%

“…Furthermore, 8 out of 10 studies were conducted in out-patient clinics [36,37,42,43,50,51,52,53], with community-dwelling individuals being recruited in two other studies [40,41]. Only one study focused on healthy individuals [40], while other studies recruited patients with social anxiety [50], moderate depression and anxiety [52], generalized anxiety disorder (GAD) [51], stress-related complaints [41], breast cancer [36,42], rheumatoid arthritis [37], heart palpitations [43], and post-menopausal BMI > 30 [53]. At least one HRV outcome was assessed in four studies, including LF [41,43,50], HF [41,43,50], LF/HF ratio [36,41,43,50], SDNN and RMSSD [36,41,43], and at least one inflammatory marker was assessed in 6 studies, including CRP [37,40,42,52,53] and IL-6 [40,42,51,53].…”

Section: Resultsmentioning

confidence: 99%

“…There were no differences in their findings if absolute power instead of normalized units of HF and LF were used. Furthermore, for study by Bower et al [42] where measures were log-transformed for all outcomes, and for study by Owens et al [43] with log-transformed results for LF/HF ratio, the corresponding means and SD were converted to raw means and SDs. The converting was made to avoid combining measures on the raw and logarithmic scales together, using the formulas provided by Fu et al [44] and Higgins et al [45].…”

Section: Methodsmentioning

confidence: 99%

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A Systematic Review and Meta-Analysis of the Impact of Mindfulness Based Interventions on Heart Rate Variability and Inflammatory Markers

Rådmark

Sidorchuk

Osika

et al. 2019

JCM

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Mindfulness Based Interventions (MBIs) have recently been increasingly used in clinical settings, and research regarding their effects on health has grown rapidly. However, with regard to the physiological effects of mindfulness practices, studies have reported associations that vary in strength and direction. Therefore, in this systematic review and meta-analysis, we aimed to systematically identify, appraise, and summarize the existing data from randomized and non-randomized controlled trials that examine physiological effects of the standardized MBIs by focusing on pro-inflammatory cytokines and C-reactive protein, and commonly used heart rate variability parameters. The following electronic databases were searched: MEDLINE (via Ovid), PsychINFO (via Ovid), PubMed, Web of Science, EMBASE, CINAHL, ProQuest (Dissertations and Theses), and Centre for Reviews and Dissemination. The systematic review identified 10 studies to be included in the meta-analysis, comprising in total 607 participants. The meta-analysis ended up with mixed and inconclusive results. This was assumedly due to the small number of the original studies and, in particular, to the lack of large, rigorously conducted RCTs. Therefore, the current meta-analysis highlights the necessity of larger, more rigorously conducted RCTs on physiological outcomes with standardized MBIs being compared to various forms of active controls, and with more long-term follow-ups.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 2 more Smart Citations

A Systematic Review and Meta-Analysis of the Impact of Mindfulness Based Interventions on Heart Rate Variability and Inflammatory Markers

Rådmark

Sidorchuk

Osika

et al. 2019

JCM

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“…We reported promising effects of medical ozone auto-hemotransfusion on the cardiovascular system injury. Pretreatment with ozone auto-hemotransfusion decreased neointimal proliferation and induced reendothelialization following a metal stent insertion (Barone et al, 2016 ). The protective mechanism whereby ozone reduces restenosis appears to involve the ozone well-described oxidative preconditioning upregulating the antioxidant enzymes, and improving the antioxidant response to an eventual injury (Barone et al, 2016 ).…”

Section: Neuroprotectionmentioning

confidence: 99%

Metabolic Syndrome and Neuroprotection

et al. 2018

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Introduction: Over the years the prevalence of metabolic syndrome (MetS) has drastically increased in developing countries as a major byproduct of industrialization. Many factors, such as the consumption of high-calorie diets and a sedentary lifestyle, bolster the spread of this disorder. Undoubtedly, the massive and still increasing incidence of MetS places this epidemic as an important public health issue. Hereon we revisit another outlook of MetS beyond its classical association with cardiovascular disease (CVD) and Diabetes Mellitus Type 2 (DM2), for MetS also poses a risk factor for the nervous tissue and threatens neuronal function. First, we revise a few essential concepts of MetS pathophysiology. Second, we explore some neuroprotective approaches in MetS pertaining brain hypoxia. The articles chosen for this review range from the years 1989 until 2017; the selection criteria was based on those providing data and exploratory information on MetS as well as those that studied innovative therapeutic approaches.Pathophysiology: The characteristically impaired metabolic pathways of MetS lead to hyperglycemia, insulin resistance (IR), inflammation, and hypoxia, all closely associated with an overall pro-oxidative status. Oxidative stress is well-known to cause the wreckage of cellular structures and tissue architecture. Alteration of the redox homeostasis and oxidative stress alter the macromolecular array of DNA, lipids, and proteins, in turn disrupting the biochemical pathways necessary for normal cell function.Neuroprotection: Different neuroprotective strategies are discussed involving lifestyle changes, medication aimed to mitigate MetS cardinal symptoms, and treatments targeted toward reducing oxidative stress. It is well-known that the routine practice of physical exercise, aerobic activity in particular, and a complete and well-balanced nutrition are key factors to prevent MetS. Nevertheless, pharmacological control of MetS as a whole and pertaining hypertension, dyslipidemia, and endothelial injury contribute to neuronal health improvement.Conclusion: The development of MetS has risen as a risk factor for neurological disorders. The therapeutic strategies include multidisciplinary approaches directed to address different pathological pathways all in concert.

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A mindfulness intervention to reduce maternal distress in neonatal intensive care: a mixed methods pilot study

Mendelson

McAfee

Damian

et al. 2018

Arch Womens Ment Health

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Mothers with an infant in the neonatal intensive care unit (NICU) are at risk for depression, anxiety, and trauma symptoms, with negative implications for maternal-infant bonding, maternal well-being, and infant development. Few interventions to promote NICU mothers' mental health, however, have been developed or tested. This pre-post pilot study assessed feasibility, acceptability, and preliminary outcomes of a mindfulness intervention for NICU mothers. Twenty-seven mothers were recruited from a university NICU and offered a mindfulness intervention via introductory video and audio-recorded practices. Participants completed a baseline self-report survey. After 2 weeks of engaging with intervention materials, participants completed a second survey and in-depth interview. Quantitative data were analyzed using paired t tests; qualitative data were analyzed using thematic coding. Twenty-four women (89%) completed the study. Quantitative data indicated significant improvements in depressive, anxiety, and trauma symptoms, negative coping, NICU-related stress, and sleep (p < 0.05). Qualitative data identified themes of perceived improvements in psychological distress and stress symptoms, self-care, and relationships. Findings support the mindfulness intervention's feasibility, acceptability, and potential promise for reducing maternal distress and promoting well-being. Use of video and audio modalities may facilitate program sustainability and scale up. Further research on the program is merited.

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A randomized controlled trial evaluating Mindfulness-Based Stress Reduction (MBSR) for the treatment of palpitations: A pilot study

Cited by 18 publications

References 10 publications

A Systematic Review and Meta-Analysis of the Impact of Mindfulness Based Interventions on Heart Rate Variability and Inflammatory Markers

A Systematic Review and Meta-Analysis of the Impact of Mindfulness Based Interventions on Heart Rate Variability and Inflammatory Markers

Metabolic Syndrome and Neuroprotection

A mindfulness intervention to reduce maternal distress in neonatal intensive care: a mixed methods pilot study

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