A Randomized controlled trial of intramuscular pentazocine compared to intravenous paracetamol for pain relief in labor at Aminu Kano Teaching Hospital, Kano

Muhammad, Zakari; Abdulrahman, Aisha; Tukur, Jamilu; Shuaibu, Samaila Adavuruku

doi:10.4103/tjog.tjog_13_17

Cited by 5 publications

(8 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is made of ethylene-vinyl acetate copolymer with a length of 40mm and a diameter of 2mm [12]. Jadelle is a set of two exible cylindrical implants consisting of dimethylsiloxane/methyl vinyl siloxane copolymer core enclosed in thin-walled silicone tubing [13]. Each rod contains 75mg of levonorgestrel and is licensed for use for 5 years [14,15].…”

Section: Introductionmentioning

confidence: 99%

“…Efforts to increase academic attainment, effective counseling on the side effects at the time of insertion, and follow up of women will impact the continuation of implants positively [6]. Also, public enlightenment on contraceptive e cacy and safety will improve its acceptance among illiterate women [13]. Clinicians also should manage bleeding problems by prescribing the combined oral contraceptive pill [15].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Early contraceptive implants removal and its associated factors among women using implants at National Referral hospital, Kampala Uganda.

Ssebatta

Kaye

Mbalinda

2020

Preprint

View full text Add to dashboard Cite

Background. Early discontinuation of implant contraceptive methods and reasons for discontinuation remains a major concern for family planning programs and is generally higher in developing countries. Discontinuation is closely related to higher rates of the overall fertility rate, unwanted pregnancies leading to possibly induced abortion. The proportion and factors associated with early contraceptive implant removal are not well known in Uganda. The objective of the study was to determine the magnitude of early implants discontinuation among women receiving implants services in the study area and the factors associated with it. Methods: A facility-based cross-sectional study was conducted from 2nd January to 3rd March 2020 through a face-to-face interview. A total of 207 Implant user women were selected by systematic random sampling technique. SPSS version 20 was used for both data entry and analysis. Factors associated with early Implant discontinuation were analyzed using a binary and multivariable logistic regression model. Variables with a p-value of <0.05 and a 95% confidence interval were considered as statistically significant. Results. The proportion of early implant discontinuation was 42%. Factors associated with early implant discontinuation included; experience of side effects (OR= 2.629; 95%CI: 1.095-6.314; P= 0.031), not having received pre-insertion counseling about the benefits and side effects of contraceptive implants (OR= 2.565; 95%CI: 1.190-5.532; P= 0.016) and staying in rural areas (OR= 2.390; 95%CI: 1.229-4.648; P= 0.010). Conclusion. Nearly one in every two mothers have early discontinuation of contraceptive implants. Factors associated with early implant removal were the experience of side effects, lack of effective counseling before insertion, and staying in rural areas. Hence, health workers should provide adequate counseling services before insertion of the implant with emphasis on possible side effects and their immediate management. Spouses, where possible, should be involved during the counselling to increase implant retention. Also proper screening of women for pregnancy before insertion of an implant should be routine.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Early contraceptive implants removal and its associated factors among women using implants at National Referral hospital, Kampala Uganda.

Ssebatta

Kaye

Mbalinda

2020

Preprint

View full text Add to dashboard Cite

show abstract

“…[16,19] Due to the IV administration, the first pass effect in the liver is by-passed leading to higher tissue concentration of the drugs, which enhances the analgesic effect of the drug. [20] Some studies have shown that pentazocine and tramadol are equally effective as pain relief in labor. [13] Average pain scores and overall mean pain score were significantly lower among women who received pentazocine compared to women who received tramadol-paracetamol.…”

Section: Discussionmentioning

confidence: 99%

“…[17] Some other studies have also found that pentazocine has better analgesic efficacy than tramadol. [20,24,25] Shetty et al (2014), in their study that compared tramadol with pentazocine, found that pain relief toward the end of first stage of labor was inadequate in both groups, though more women in the pentazocine group reported moderately severe pain compared to the tramadol group who reported severe pain. [13] The APGAR scores and the need for SCBU admission were statistically comparable in the tramadol-paracetamol and pentazocine groups.…”

Section: Discussionmentioning

confidence: 99%

Pentazocine versus tramadol-paracetamol combination as analgesia in labor: A randomized controlled trial

Opadiran

Isah

Offiong

et al. 2022

ANMRP

View full text Add to dashboard Cite

Objectives: Labor should be a satisfactory experience and effective pain management should be employed as recommended by the American Congress of Obstetricians and Gynaecologists. In developing countries, pain management in labor is still a big challenge and the search for the ultimate labor analgesia is still ongoing. The objectives of the study were to determine whether the synergistic analgesic effect of the combination of tramadol and paracetamol will produce analgesia comparable to pentazocine with a better side effect profile. Material and Methods: This was a randomized controlled, double-blinded trial of tramadol-paracetamol combination versus pentazocine as labor analgesia and was carried out at the University of Abuja Teaching Hospital, Abuja, between June 2018 and March 2019. A total of 218 eligible parturients recruited at term, were counseled on labor analgesia, its benefits, and the options made available to them and educated on the pain scoring system. Parturients were allocated into two groups using computer-generated numbers with the WINPEPI software. Group A was given tramadol-paracetamol combination, while Group B received pentazocine, both at standard doses. Hourly pain scores, APGAR scores, labor duration, patients’ satisfaction, and side effects were collated. The level of significance was set at <0.05. Results: Tramadol-paracetamol was administered to 109 (50.9%) while pentazocine was administered to 105 (49.1%) of the study participants. The mean age in the tramadol-paracetamol group was 29.6 ± 4.8 years, and in the pentazocine group, it was 28.8 ± 4.5 years. The difference in pain scores on the visual analog scale was statistically significant at the 3rd and 4th h (P = 0.02 and 0.004), but not significant in the 1st and 2nd h (P = 0.05 and 0.22) in the two groups. Overall, the average pain score in the tramadol-paracetamol group was significantly higher compared to the pentazocine group (5.27 ± 1.86 vs. 4.72 ± 1.54; P = 0.02). The 1st and 5th min APGAR scores (P = 0.44 and 0.67, respectively) of neonates in the tramadol-paracetamol and pentazocine groups were comparable. Nausea and drowsiness occurred more frequently in the pentazocine group at P-values of 0.047 and 0.0015, respectively. There was no statistically significant difference in the duration of labor between the tramadol-paracetamol and pentazocine groups. not statistically significant, a higher proportion of parturients in the pentazocine group was satisfied compared with the tramadol-paracetamol group (71.4% vs. 63.3%; P = 0.13). Conclusion: This study showed that intravenous pentazocine provides better pain relief in labor, but the tramadol-paracetamol combination has fewer side effects.

show abstract

“…Women have reported receiving positive and negative support from birthing professionals [4]. Women often choose different coping strategies to reduce labor pain, including both pharmacological and non-pharmacological, or more natural, strategies [5]. The non-pharmacological coping strategies refer to methods other than medication that is designed to reduce labor pain [9][10][11][12][13][14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Effects of non-pharmacological coping strategies for reducing labor pain: A systematic review and network meta-analysis

et al. 2022

View full text Add to dashboard Cite

Background Facilitating the childbirth process is a global issue. Many strategies have been developed to cope with labor pain and improve the delivery experience and satisfaction of pregnant women. The results of different types of medical intervention on women’s expectant pain have been varied. Therefore, this systematic review was aimed at summarizing the body of evidence regarding the effects of various non-pharmacological coping strategies for reducing labor pain. Methods The review was conducted according to guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We systematically searched the articles published between 1989 and 2020 in six electronic databases: PubMed, MEDLINE, CINAHL, WOS, PsycARTICLES, and Airiti Library, and the reference lists of the Clinical Trial Registry. Twenty studies were identified, with eight eligible studies included in the Bayesian network meta-analysis. Results Eight studies with 713 participants were included in the meta-analysis with nine different non-pharmacological strategies for reducing labor pain. The traditional meta-analysis demonstrated that the non-pharmacological coping strategies were effective in reducing labor pain. Of these interventional strategies, the ranking probabilities analysis of the network meta-analysis suggested that the Bonapace Method may be the most effective strategy in reducing labor pain, followed by acupressure. Conclusions Non-pharmacological coping strategies can reduce labor pain while maintaining an effective and satisfactory delivery experience. This systematic review, by synthesizing the body of evidence, demonstrated that non-pharmacological coping strategies are effective in reducing labor pain. Furthermore, as demonstrated in the network meta-analysis, the Bonapace Method, modulating birth pain by involving the father, is the most effective non-pharmacological intervention for reducing labor pain.

show abstract

A Randomized controlled trial of intramuscular pentazocine compared to intravenous paracetamol for pain relief in labor at Aminu Kano Teaching Hospital, Kano

Cited by 5 publications

References 2 publications

Early contraceptive implants removal and its associated factors among women using implants at National Referral hospital, Kampala Uganda.

Early contraceptive implants removal and its associated factors among women using implants at National Referral hospital, Kampala Uganda.

Pentazocine versus tramadol-paracetamol combination as analgesia in labor: A randomized controlled trial

Effects of non-pharmacological coping strategies for reducing labor pain: A systematic review and network meta-analysis

Contact Info

Product

Resources

About