2020
DOI: 10.1016/j.drugalcdep.2020.108149
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A randomized pilot trial of topiramate for alcohol use disorder in veterans with traumatic brain injury: Effects on alcohol use, cognition, and post-concussive symptoms

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Cited by 8 publications
(5 citation statements)
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“…Following screening and retrieval, 19 articles were evaluated for inclusion in the investigation (Figure 1). Of the 19, 13 RCTs (Anthenelli et al, 2017; Baltieri et al, 2008; Batki et al, 2014; Johnson et al, 2003, 2007; Kampman et al, 2013; Knapp et al, 2015; Kranzler et al, 2014; Likhitsathian et al, 2013; Martinotti et al, 2014; Pennington et al, 2020; Rubio et al, 2009; Sylvia et al, 2016) were considered for the quantitative analysis. However, we extracted data on GGT concentrations from Johnson et al (2004) and adverse effects not reported elsewhere from Kranzler et al (2021).…”
Section: Resultsmentioning
confidence: 99%
“…Following screening and retrieval, 19 articles were evaluated for inclusion in the investigation (Figure 1). Of the 19, 13 RCTs (Anthenelli et al, 2017; Baltieri et al, 2008; Batki et al, 2014; Johnson et al, 2003, 2007; Kampman et al, 2013; Knapp et al, 2015; Kranzler et al, 2014; Likhitsathian et al, 2013; Martinotti et al, 2014; Pennington et al, 2020; Rubio et al, 2009; Sylvia et al, 2016) were considered for the quantitative analysis. However, we extracted data on GGT concentrations from Johnson et al (2004) and adverse effects not reported elsewhere from Kranzler et al (2021).…”
Section: Resultsmentioning
confidence: 99%
“…Traumatic brain injuries must be addressed promptly and treated based on their etiology and presenting symptoms. Topiramate is a medication that may be used to treat various pathologies, including alcohol use disorder and TBI [ 13 ]. Given our patient's presentation, this medication was appropriate for initially managing the presumptive underlying condition.…”
Section: Discussionmentioning
confidence: 99%
“…Topiramate has also been shown to be potentially effective, although it has not been approved by the FDA for the treatment of alcohol dependence (Anton, 2008;Kranzler, Soyka, 2018;Pennington et al, 2020). Off label, topiramate can be considered for those with AUD (Fairbanks et al, 2020).…”
Section: Discussionmentioning
confidence: 99%