A Randomized Prospective Study of Rehabilitation Therapy in the Treatment of Radiation-induced Dysphagia and Trismus

Tang, Yamei; Shen, Qingyu; Wang, Y.; Lü, Ke; Peng, Yinglin

doi:10.1007/s00066-010-2151-0

Cited by 95 publications

(120 citation statements)

References 26 publications

Supporting

Mentioning

115

Contrasting

Unclassified

Order By: Relevance

“…The participants that did not undergo TC Qigong training demonstrated a dramatic decrease in interincisor distance over the 12-month study period (Table 3). Our findings concur with those of Tang et al 6 who reported that trismus progressed quickly in NPC patients if no rehabilitation was received. They found that therapeutic exercises (TMJ active ROM exercises) prevented the progression of trismus in NPC patients after radiotherapy.…”

Section: Discussionsupporting

confidence: 93%

“…1 Currently, the primary medical management for NPC is radiotherapy, while chemotherapy and surgery (eg, nasopharyngectomy) are elective treatments. 2 Although previous research has shown that these aggressive treatment methods can successfully control tumors and thus increase overall survival rates, 1 survivors generally experience many associated side effects, such as neck muscle fibrosis, 3,4 trismus or restricted mouth opening, 5,6 and shoulder dysfunctions. 7 The disease can also directly cause chronic symptoms, such as pain and fatigue.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The Effects of a 6-Month Tai Chi Qigong Training Program on Temporomandibular, Cervical, and Shoulder Joint Mobility and Sleep Problems in Nasopharyngeal Cancer Survivors

Fong

Lee

et al. 2014

Integr Cancer Ther

View full text Add to dashboard Cite

Introduction. Nasopharyngeal cancer (NPC) survivors often sustain head-neck-shoulder impairments from conventional treatments, which could disturb sleep. This novel study aimed to examine the efficacy of Tai Chi (TC) Qigong in optimizing temporomandibular joint (TMJ), cervical, and shoulder joint mobility and reducing sleep problems in NPC survivors. Methods. Fifty-two NPC survivors participated in the study. The experimental group (n = 25) received 6 months of TC Qigong training (1.5 h/session; 4 sessions/wk including self-practice) while the control group (n = 27) received no training. Cervical side flexion and rotation, shoulder flexion and horizontal flexion range of motion (ROM), mouth opening capacity (interincisor distance), and sleep problems (Medical Outcomes Study Sleep Scale) were assessed at baseline, mid-intervention (3 months), immediately after TC Qigong training, and at 6-month follow-up. Results. Intention-to-treat analysis revealed improvement in cervical side flexion ROM only (P < .008) and unchanged shoulder and TMJ mobility (P > .008) after the TC Qigong training. Deterioration was observed in shoulder flexion ROM and mouth opening capacity in the no-training controls over time (P < .008). Sleep problems also decreased in the TC Qigong group (P < .008), and this effect was most profound during the follow-up period. In addition, improvement in cervical side flexion ROM was associated with a reduction in sleep problems in the experimental group after TC Qigong training (P < .05). Conclusions. The 6-month TC Qigong intervention improved neck mobility, maintained TMJ and shoulder joint mobility, and reduced sleep problems for NPC survivors. TC Qigong could be an effective nonpharmacological intervention for managing progressive trismus, chronic neck and shoulder hypomobility, and reducing sleep problems among NPC survivors.

show abstract

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

The Effects of a 6-Month Tai Chi Qigong Training Program on Temporomandibular, Cervical, and Shoulder Joint Mobility and Sleep Problems in Nasopharyngeal Cancer Survivors

Fong

Lee

et al. 2014

Integr Cancer Ther

View full text Add to dashboard Cite

show abstract

“…Several studies 24,42,53,54 have reported that the prevention of trismus instead of its treatment is the most desirable objective since the radiation-induced trismus is of difficult to recover. Therefore, early intervention of a physiotherapist, who is inserted in the multidisciplinary team working in the care of cancer patient, becomes extremely necessary to prevent or to reduce this frequent complication, with is occasionally ignored but with significant negative impact on the quality of life of patients with H&NC.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of acute radiation effects on mandibular movements of patients with head and neck cancer

Bragante

Nascimento

Motta

2012

Rev. bras. fisioter.

View full text Add to dashboard Cite

“…Since the patient had no history which might induce stroke, we strongly speculate the symptom rather rendered by radiation therapy than other causes. Although some treatment of ischemic stroke and radiation-induced brain injury is similar such as rehabilitation training [6], thrombolysis and interventional therapy are not routine treatment for radiation-induced brain injury. Given early diagnosis, clinicians might use thrombolysis, vascular angioplasty or stenting to make the patient get better prognosis before the vascular completely blocked.…”

Section: Case Reportmentioning

confidence: 99%

Wallenberg Syndrome Caused by Radiation-Induced Brain Injury: Case Report

P¹

2017

Austin J Cerebrovasc Dis & Stroke

View full text Add to dashboard Cite

Radiation-induced brain injury, being a serious complication after radiotherapy, is a disease of nervous system damage caused by radiation therapy for patients with head and neck cancer. Since radiation therapy can cause large blood vessel stenosis or blockage, when it damages the brain stem, Wallenberg syndrome may appear.We report a case of Wallenberg syndrome induced by radiation therapy.Wallenberg syndrome caused by radiation-induced brain injury is easy for clinicians to miss diagnosis or misdiagnose. Early head MR examination plays a pivotal role in reduce its occurrence rate. Clinicians should be vigilant of the blocked vascular caused by radiation therapy and initiate early thrombolysis, vascular angioplasty or stenting to make the patients get better prognosis.Keywords: Wallenberg syndrome; Radiation-induced brain injury; Miss diagnose; Misdiagnose pressure was 174/97mmHg, the right pupil measured 2.5 mm, the left pupil measured 3.0 mm, both pupils were sensitive to light, the right side of the nose was slightly shallow, the tongue extended to the right and pharyngeal reflex disappeared. CT scan of the brain ( Figure 1A) showed radiation-induced bilateral temporal lobe lesions with no abnormalities in the brain stem. Cervical computed tomography angiography (CTA) ( Figure 1B) was performed after neck vascular ultrasound indicating that the right vertebral artery may be embolized, and the right vertebral artery was proved to be occluded by the CTA. The contrast-enhanced magnetic resonance imaging (MRI) and fluidattenuated inversion recovery (FLAIR) ( Figure 1C-1I) demonstrated an acute infarction in the right medulla and radiation-induced brain injury in bilateral temporal lobe.After his admission to the hospital, he got the treatment of antiplatelet agents, neuroprotective drugs and other symptomatic support treatment. Fifty days later, the patient was out of the hospital with a nasogastric tube, and neurologic examination showed that pharyngeal reflex disappeared.Informed consent was obtained from the patient and this case study was approved by the hospital ethical committee. DiscussionTo our knowledge, this is the first case report of Wallenberg syndrome caused by radiation-induced brain injury.The patient's brain CT scan did not show the brain stem lesions in his first visit to a hospital. With the progress of the disease, the medullary infarction was finally demonstrated by the contrastenhanced MRI, which still had not been observed by the second CT scan of the brain. In fact, the patient was likely to have been at the early stage of cerebral infarction at his first visit to the hospital according to his symptoms. However, due to the limitations of brain CT in the diagnosis of brain stem lesions and the diversity of the symptoms of Case PresentationRadiation-induced brain injury, being a serious complication after radiotherapy, is a disease of nervous system damage caused by radiation therapy for patients with head and neck cancer [1]. Since radiation therapy can cause large blood vessel s...

show abstract

A Randomized Prospective Study of Rehabilitation Therapy in the Treatment of Radiation-induced Dysphagia and Trismus

Abstract: Rehabilitation training can improve swallow function and slow down the progress of trismus in NPC patients following radiotherapy.

Cited by 95 publications

References 26 publications

The Effects of a 6-Month Tai Chi Qigong Training Program on Temporomandibular, Cervical, and Shoulder Joint Mobility and Sleep Problems in Nasopharyngeal Cancer Survivors

The Effects of a 6-Month Tai Chi Qigong Training Program on Temporomandibular, Cervical, and Shoulder Joint Mobility and Sleep Problems in Nasopharyngeal Cancer Survivors

Evaluation of acute radiation effects on mandibular movements of patients with head and neck cancer

Wallenberg Syndrome Caused by Radiation-Induced Brain Injury: Case Report

Contact Info

Product

Resources

About