A randomized, single-blinded, prospective study that compares complications between cuffed and uncuffed nasal endotracheal tubes of different sizes and brands in pediatric patients

Armendi, Alberto J. de; Butt, Amir L.; Shukry, Mohanad; Cure, Jorge A.; Hollabaugh, Kimberly

doi:10.1016/j.jclinane.2014.11.003

Cited by 3 publications

(2 citation statements)

References 23 publications

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“…A total of 521 articles were obtained by preliminary search and screening, and 225 articles were excluded after review, analysis, and evaluation excluding systematic review, meta‐analysis, review literature and animal experiment articles, 216 articles were excluded by reading abstracts. Finally, nine 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 articles were screened, resulting in 11 068 patients, 7391 in the cuff group, and 3677 in the non‐cuff group. Figure 1 illustrates the document screening process.…”

Section: Resultsmentioning

confidence: 99%

Meta‐analysis of the influence of tracheal intubation with cuff and without cuff on the incidence of total wound complications in ICU intubation patients

Jiang,

Wang,

et al. 2024

International Wound Journal

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At present, it is still controversial whether patients in intensive care unit (ICU) use tracheal intubation with or without cuff. This paper evaluates the effect of tracheal intubation with and without cuff on overall complication rate of patients with intubation in ICU. The database of PubMed, Embase, Conchrane Library and Web of Science was searched by computer, and the clinical research on intubation with and without cuff in ICU was collected. The time range was from the database establishment to November 2023. Literature was independently screened, information was extracted, and quality was assessed by two researchers. Finally, there were nine studies included, with 11 068 patients (7391 in cuff group and 3677 in non‐cuff group). The results showed that the overall complication rate of cuff group was significantly lower than that of non‐cuff group, and that of cuff group (RR = 0.53, p < 0.01). In addition, compared with the non‐cuff group, the cuff group had a lower number of tracheal intubation changes [RR = 0.05, p < 0.01] and a lower incidence of aspiration pneumonia (RR = 0.45, p = 0.01). Compared with the non‐cuff group, the cuff group had a higher incidence of oral mucosal ulcers and pharyngitis (RR = 1.99, p = 0.04), while the cuff group had a lower incidence of laryngeal edema (RR = 0.39, p < 0.01). In ICU intubation patients, the use of cuffs reduces overall complication rate in comparison to patients without cuffs. Therefore, patients with intubation in ICU can recommend tracheal intubation with cuff.

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Section: Resultsmentioning

confidence: 99%

Meta‐analysis of the influence of tracheal intubation with cuff and without cuff on the incidence of total wound complications in ICU intubation patients

Jiang,

Wang,

et al. 2024

International Wound Journal

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“…We systematically searched for and reviewed 10 randomised controlled trials in children in whom cuffed tracheal tubes were changed one‐sixth as often as uncuffed tubes, relative risk (95%CI) 0.17 (0.07–0.41), p < 0.001 (Fig. ) .…”

Section: An Updated Meta‐analysismentioning

confidence: 99%

Cuffed tracheal tubes: guilty now proven innocent

Shah

Carlisle

2019

Anaesthesia

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Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under

Orange

Andrade

Lemos

et al. 2017

Cochrane Database of Systematic Reviews

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Implications for practiceWe are unable to draw definitive conclusions about the comparative effects of cuffed or non-cuffed endotracheal tubes in children undergoing general anaesthesia. Our confidence is limited by risks of bias, imprecision and indirectness. The lower requirement for exchange of tubes with cuffed ETTs was very low-quality evidence, and the requirement for less medical gas used and consequent lower cost was low-quality evidence. In some cases, tracheal re-intubation is required to guarantee an open airway when adequate oxygenation is difficult after removal of the tube, for a variety of reasons including stridor, muscle weakness or obstruction. No data were available to permit evaluation of whether appropriate tidal volumes were delivered. Implications for researchLarge randomized controlled trials of high methodological quality should be conducted to help clarify the risks and benefits of cuffed ETTs for children. Such trials should investigate the capacity to deliver appropriate tidal volume. Future trials should also address cost effectiveness and respiratory complications. Such studies should correlate the age of the child with the duration of intubation, and with possible complications. Studies should also be conducted in newborn babies. Future research should be conducted to compare the effects of the different types or brands of cuffed tubes used worldwide. Finally, trials should be designed to perform more accurate assessments and to diagnose the complications encountered with cuffed compared to uncuffed ETTs.

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A randomized, single-blinded, prospective study that compares complications between cuffed and uncuffed nasal endotracheal tubes of different sizes and brands in pediatric patients

Cited by 3 publications

References 23 publications

Meta‐analysis of the influence of tracheal intubation with cuff and without cuff on the incidence of total wound complications in ICU intubation patients

Meta‐analysis of the influence of tracheal intubation with cuff and without cuff on the incidence of total wound complications in ICU intubation patients

Cuffed tracheal tubes: guilty now proven innocent

Cuffed versus uncuffed endotracheal tubes for general anaesthesia in children aged eight years and under

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