A randomized study to assess two different techniques of aspiration while performing transabdominal chorionic villus sampling

Abstract

ABSTRACT

Chorionic villus vacu‐sampling in 377 consecutive cases

“…Our results demonstrate the technical feasibility of chorionic villus vacu-sampling, with 100% adequate yield with a single pass, a 5.3% retrieval of <5 mg and a fetal loss rate before 22 weeks of 0.73%. Such results compare favorably with those of the only other published series using a similar technique (Battagliarin et al, 2009). That randomized study found no significant differences in the size of chorionic samples between use of CVS vacu-sampling compared with the classic syringe and hand-grip device to create vacuum.…”

“…We (Calda et al, 2007) as well as others (Battagliarin et al, 2009) have also successfully applied the same negative pressure vacuum tube system to CVS, a technique that we have named 'chorionic villus vacusampling'. We now report our experience with this technique at our center.…”

ISUOG Practice Guidelines: invasive procedures for prenatal diagnosis

“…A single needle of 17–20 G or a two‐needle set of outer 17/19 G and inner 19/20 G may be used ( EVIDENCE LEVEL: 1– ). Once the needle has reached the target within the placenta, between one and 10 back‐and‐forth movements are performed, while the vacuum is maintained and samples are aspirated either manually by an assistant or with a vacuum adaptor.…”

Modeling chorionic villus sampling technique: influence of number of needle ‘passes’ on quantity of chorionic villi obtained

“…In particular, the number of times that the CVS needle is advanced and withdrawn while within the placental tissue, i.e. the number of needle 'passes', varies between operators, from one to 20 times having been reported 2,3,5 . We have developed a model to test differences in CVS technique, and used it to determine if the number of needle passes influences the quantity of chorionic villi aspirated.…”