A rare case of aortic dissection presenting as pure transient global amnesia

Kaveeshvar, Hirsh; Kashouty, Rabih; Loomba,; Yono, Noor

doi:10.5830/cvja-2015-061

Cited by 8 publications

(4 citation statements)

References 9 publications

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“…Other causes of such disease states are ruled out prior to reaching the diagnosis of TGA ( Figure 1 ). 110 , 111 …”

Section: Differential Diagnosismentioning

confidence: 99%

Transient global amnesia: current perspectives

Spiegel¹,

Smith²,

Wade³

et al. 2017

NDT

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Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of an extraordinarily large reduction of anterograde and a somewhat milder reduction of retrograde episodic long-term memory. Additionally, executive functions are described as diminished. Although it is suggested that various factors, such as migraine, focal ischemia, venous flow abnormalities, and epileptic phenomena, are involved in the pathophysiology and differential diagnosis of TGA, the factors triggering the emergence of these lesions are still elusive. Recent data suggest that the vulnerability of CA1 neurons to metabolic stress plays a pivotal part in the pathophysiological cascade, leading to an impairment of hippocampal function during TGA. In this review, we discuss clinical aspects, new imaging findings, and recent clinical–epidemiological data with regard to the phenotype, functional anatomy, and putative cellular mechanisms of TGA.

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“…Other causes of such disease states are ruled out prior to reaching the diagnosis of TGA ( Figure 1 ). 110 , 111 …”

Section: Differential Diagnosismentioning

confidence: 99%

Transient global amnesia: current perspectives

Spiegel¹,

Smith²,

Wade³

et al. 2017

NDT

View full text Add to dashboard Cite

show abstract

“…Timely ED detection of the seldom encountered, but highly lethal, condition of thoracic AoD is critical yet challenging given the considerable range of symptomatology 1–5 . Our case provides a very rare description of painless AoD presenting as pure TGA, which has only been communicated in a few previous reports 6–12 . Emergency physicians should specifically recognize thoracic AoD as a potential underlying etiology of TGA‐like syndromes.…”

Section: Diagnosismentioning

confidence: 85%

“…[1][2][3][4][5] Our case provides a very rare description of painless AoD presenting as pure TGA, which has only been communicated in a few previous reports. [6][7][8][9][10][11][12] Emergency physicians should specifically recognize thoracic AoD as a potential underlying etiology of TGA-like syndromes. The use of FOCUS in evaluating undifferentiated hypotension and a multitude of cardiovascular emergencies including AoD has been well-described.…”

Section: Thoracic Aortic Dissectionmentioning

confidence: 99%

Bedside echocardiography evaluation of a male with transient global amnesia

Dewberry¹,

Kalivoda²,

Correa³

et al. 2022

JACEP Open

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“…So far, nine cases with acute ADA and amnesia have been described, as listed in the table. [1][2][3][4][5][6][7] Six of these nine patients experienced anterograde amnesia in the form of a TGA. However, in none of the previously published cases, an activity associated with increased intrathoracic pressure has been reported.…”

Section: Discussionmentioning

confidence: 99%

Anterograde Amnesia as a Manifestation of Acute Type A Aortic Dissection

et al. 2019

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Objectives Memory impairment has been only rarely reported in association with acute aortic dissection type A. We report a patient with pure anterograde amnesia and memory impairment of contents occurring after the event, accompanying acute aortic dissection type A. Case Report A previously healthy 53-year-old Caucasian male was admitted because of sudden chest pain after having lifted a heavy object. Clinical examination and electrocardiogram showed no abnormalities. Since blood tests showed leukocytosis, anemia, and elevated D-dimer level, either pulmonary embolism or aortic dissection was suspected; therefore, computed tomography was suggested. The patient seemed disoriented to time, and neurologic investigation confirmed that the patient was disoriented to time; short time memory was severely impaired and concentration was reduced. An amnestic episode with anterograde amnesia was diagnosed. Computed tomography showed type A aortic dissection. A supracoronary replacement of the ascending aorta was performed. The patient was discharged on the 7th postoperative day. Three months postoperatively, the patient is clinically stable; however, amnesia for the interval between pain onset and cardiac surgery persists. Conclusions Transient amnesia, usually considered a benign syndrome, may be more common than generally recognized in aortic dissection. The suspicion for aortic dissection or other cardiovascular emergencies is substantiated when amnesia is associated with sudden onset of chest pain, leukocytosis, and elevated D-dimer levels. Computed tomography of the aorta with contrast medium is the imaging method of choice to confirm or exclude the diagnosis.

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A rare case of aortic dissection presenting as pure transient global amnesia

Cited by 8 publications

References 9 publications

Transient global amnesia: current perspectives

Transient global amnesia: current perspectives

Bedside echocardiography evaluation of a male with transient global amnesia

Anterograde Amnesia as a Manifestation of Acute Type A Aortic Dissection

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