A Rare Case of Benign Luteomas of Pregnancy Masquerading as Malignancy

Devlin, Kelly M.; Payton, Amber; Rubino, Jessica M.; Shapiro, Robert E.

doi:10.1177/8756479320905864

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…In a study where 18 cases of pregnancy luteomas were studied in multiple pregnancies the gross, immune histochemical and reticular fiber stain may help diagnose the disease. 8 Luteoma of pregnancy is often mistaken for having malignant potential and sometimes resulted in surgical removal during 1st trimester. 9 So, detailed workup of every adnexal mass during pregnancy is important.…”

Section: Discussionmentioning

confidence: 99%

Luteoma in pregnancy: a rare cause of threatened preterm labour!

Mishra

Rane

Chhetry

et al. 2023

Int J Reprod Contracept Obstet Gynecol

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Pregnancy luteoma is a rare non-neoplastic tumor-like mass of the ovary. They are usually asymptomatic and found incidentally during ultrasound imaging or surgery. Rarely do they present with pain abdomen mimicking threatened preterm labor. They regress spontaneously after delivery. We presented a case of a 29-year-old G4A3 with twin pregnancies and chronic hypertension who presented with acute flank pain, constipation, and occasional hardening of the uterus. A provisional diagnosis threatened preterm labor with suspected ureteric colic and cystitis was made. The patient was initially managed on the same line but on a detailed in-patient evaluation her ultrasound revealed bilateral multicystic ovaries with few hypoechoic areas inside it mostly suggestive of ‘luteoma of pregnancy’. The patient had acne, hirsutism, and chronic hypertension well controlled on antihypertensives. The patient delivered twins successfully by cesarean section and luteoma and symptoms were resolved postpartum after 4 months. Recognition of this entity is important so that malignancy can be ruled out and unnecessary surgery, with concomitant risk to both the mother and the fetus, is avoided.

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Section: Discussionmentioning

confidence: 99%

Luteoma in pregnancy: a rare cause of threatened preterm labour!

Mishra

Rane

Chhetry

et al. 2023

Int J Reprod Contracept Obstet Gynecol

View full text Add to dashboard Cite

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Is Ultrasound a Reliable and Reproducible Method for Assessing Adnexal Masses in Pregnancy? A Systematic Review

Gaughran¹,

Naji²,

Sabbagh³

et al. 2021

Cureus

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In this study, we aimed to systematically review the current evidence regarding the diagnostic accuracy of ultrasound in assessing adnexal masses in pregnancy. The Cochrane Register of Controlled Trials, PubMed, and EMBASE databases were searched for all types of clinical studies that utilised ultrasound for the diagnosis of adnexal masses in pregnancy. Only studies that used outcome measures of either histological diagnosis or significant regression of the adnexal mass on imaging follow-up were included. The quality of each study was assessed for risk of bias. The diagnostic performance of ultrasound in each study type was calculated, along with the pooled diagnostic performance of ultrasound in differentiating benign from malignant masses. The initial search yielded 4,915 articles, of which 2,547 qualified for abstract screening. A total of 83 articles were included in this review, including one prospective cohort study, six retrospective observational studies, seven case series, and 69 case reports. In the included studies, the total number of adnexal masses was 559. The mean patient age was 29.2 years (95% confidence interval [CI]: 28.7-29.7), with a mean gestational age at diagnosis of 13.8 weeks (95% CI: 13.2-14.4). The mean quality assessment score was 75%. The International Ovarian Tumour Analysis Simple Rules were used in two articles, whereas subjective impression was used in the remaining 81 articles. The most frequently diagnosed mass was a simple or physiological cyst (35%). The prevalence of malignancy in the entire sample was 46/559 (8%; 95% CI: 34-61%). The overall pooled sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of ultrasound in detecting ovarian malignancy were 64% (95% CI: 30-88%), 88% (95% CI: 64-97%), 5.6 (95% CI: 1.2-25.4), and 0.4 (95% CI: 0.15-1), respectively. In conclusion, currently, there is a lack of highquality prospective studies to guide the management of adnexal masses in pregnancy. Ultrasound appears to have an adequate accuracy in differentiating benign from malignant masses; however, more research is required to assess the role of ultrasound models, rules, and subjective assessment in pregnancy compared to non-pregnant women.

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A Rare Case of Benign Luteomas of Pregnancy Masquerading as Malignancy

Cited by 2 publications

References 14 publications

Luteoma in pregnancy: a rare cause of threatened preterm labour!

Luteoma in pregnancy: a rare cause of threatened preterm labour!

Is Ultrasound a Reliable and Reproducible Method for Assessing Adnexal Masses in Pregnancy? A Systematic Review

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