A rare case of bilateral synchronous spermatocytic tumours in a young man seeking fertility preservation

Østergren, Peter Busch; Salami, Simpa S.; Udager, Aaron M.; Sønksen, Jens; Ohl, Dana A.; Palapattu, Ganesh S.

doi:10.1080/21681805.2016.1249515

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…Two case reports of PO in a solitary testis both resulted in azoospermia 38,39 together with hypogonadism in one case in (testosterone 145 ng/dL) 39 . Hallak et al also reported two cases of TSS in single testes with a decrease in testosterone in one patient in their series to 195 ng/dL 34 .…”

Section: Fertility and Endocrine Function Following Partial Orchidectomymentioning

confidence: 94%

The role of partial orchidectomy in the management of small testicular tumours: Fertility and endocrine function

et al. 2020

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Background Radical orchidectomy in patients who are subsequently diagnosed with benign testicular tumours represents an overtreatment due to the deleterious effects on endogenous testosterone, fertility and body image. For these reasons, the option of partial orchidectomy (PO) should be considered in certain groups of patients. Patients with bilateral tumours (synchronous or metachronous) or a solitary testis where the lesion is no greater than 30% of the volume of the testis could be considered for a PO. Evidence has shown that PO is effective for small testicular masses with excellent survival and recurrence rates. Objectives Highlight the feasibility of maintaining post‐operative fertility or normal semen parameters and endocrine function following PO. Materials and Methods Data for this review were obtained through a search of the PubMed database. Papers were required to be in English and focus on adult human males. Results Eligible and relevant papers were assessed for data regarding fertility, semen parameters and endocrine function following PO for a small testicular mass (STM). Conclusion It is possible to preserve both fertility and endocrine function after PO. Although patients may still require adjuvant radiotherapy for concomitant intratubular germ cell neoplasia (ITGCN) which results in subfertility, endocrine function is still conserved. However, it is possible to postpone radiotherapy and continue with clinical surveillance for the purposes of fertility preservation.

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Section: Fertility and Endocrine Function Following Partial Orchidectomymentioning

confidence: 94%

The role of partial orchidectomy in the management of small testicular tumours: Fertility and endocrine function

et al. 2020

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Outcomes of organ‐sparing surgery for adult testicular tumors: A systematic review of the literature

et al. 2021

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Objective To perform a systematic review on the effects of testicular sparing surgery (TSS) on the oncological, functional, and hormonal outcomes of adults with testicular tumors. Methods A literature search was performed after PROSPERO registration (CRD42020200842) and reported in compliance with Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) methods. We conducted a systematic search of Medline (Ovid), Embase, Cochrane CENTRAL, CINAHL, Scopus, Web of Science, ClinicalTrials.gov, and the WHO/ICTRP from inception to November 20, 2020. Manuscripts and published abstracts were included if they involved testis‐sparing surgery (TSS) and contained data on any outcomes related to fertility, hormonal parameters, or oncological control, or if they evaluated surgical technique. Results Our initial search yielded 3,370 manuscripts, with 269 of these screened for full‐text eligibility. After our exclusion criteria were applied, 32 studies were included in the final analysis. Oncological outcomes were obtained from 12 studies (average follow‐up 57.8 months), functional data from 26 studies (average follow‐up 49.6 months), fertility information from 10 studies (average follow‐up 55.8 months), and data on nonpalpable tumors from 11 studies (average follow‐up 32.1 months). Oncological control appears to be excellent in studies that reported these outcomes. Presence of germ cell neoplasia in situ was controlled with adjuvant radiation in nearly all cases. Functional outcomes are also promising, as development of primary and compensated hypogonadism was rare. Semen parameters are poor preoperatively among men with benign and malignant testis tumors, with occasional decline after TSS. Frozen section analysis at the time of surgery appears to be very reliable, and the majority of nonpalpable tumors appear to be benign. Conclusions TSS is a safe and efficacious technique with regards to oncological control and postoperative hormonal function based on retrospective, noncontrolled studies. TSS avoids unnecessary removal of benign testicular tissue, and should be given serious consideration in cases of nonpalpable, small tumors under 2 cm. In cases of malignancy, TSS can safely avoid anorchia in men with bilateral tumors and in men with solitary testicles. The use of the operating microscope, while theoretically promising, does not necessarily lead to better outcomes, however data are limited.

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Spermatocytic tumor with extensive lymphovascular invasion in a young male

Chawhan,

Ahluwalia,

Ahuja

2024

Urology Case Reports

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A rare case of bilateral synchronous spermatocytic tumours in a young man seeking fertility preservation

Cited by 3 publications

References 5 publications

The role of partial orchidectomy in the management of small testicular tumours: Fertility and endocrine function

The role of partial orchidectomy in the management of small testicular tumours: Fertility and endocrine function

Outcomes of organ‐sparing surgery for adult testicular tumors: A systematic review of the literature

Spermatocytic tumor with extensive lymphovascular invasion in a young male

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