A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon

Watanabe, Taiji; Segami, Kohei; Sasaki, Takahiro; Kawashima, Hatsuya; Enomoto, Takeharu; Jinnouchi, Yuji; Koizumi, Satoshi; Tobe, Naotaka; Sakurai, Joe; Shimamura, Tsuyoshi; Suda, Tadashi; Asakura, Takeshi; Nakano, Hiroshi; Ichiroh, Tanaka; Otsubo, Takehito

doi:10.1186/1477-7819-5-59

Cited by 5 publications

(4 citation statements)

References 17 publications

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“…Despite their rarity, these tumors are the most common GI mesenchymal tumors [ 1 ]. The GISTs growth pattern can be intramural, intraluminal and exophytic [ 3 ]. Exophytic lesions are the most common and occur in 68-79% cases [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

“…They mostly present with GI bleeding and symptoms related to adjacent organ compression by the tumor, however, patients can be asymptomatic. The GISTs growth pattern can be intramural, intraluminal and exophytic [ 3 ]. We present a unique case of GIST where despite the large size of the tumor, it lacked suggestive endoscopic manifestations.…”

Section: Introductionmentioning

confidence: 99%

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Gastrointestinal Stromal Tumors: Deception to the Eyesight

Haddad

Daoud

Kesavan

et al. 2017

Cureus

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Gastrointestinal stromal tumors (GISTs) are rare soft tissue tumors. Despite their rarity, these tumors are the most common gastrointestinal (GI) mesenchymal tumors. They can involve various parts of the gastrointestinal tract. GISTs growth can be intramural, intraluminal or exophytic. Symptoms are usually related to GI bleeding and to adjacent organ compression by the tumor. Endoscopy can suggest the diagnosis, but tissue sampling is required for the diagnosis. Herein, we present a unique case of GIST where the patient had negative endoscopic findings despite the large size of the tumor, thus abdominal computed tomography scan and endoscopic ultrasound was required to make the diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Gastrointestinal Stromal Tumors: Deception to the Eyesight

Haddad

Daoud

Kesavan

et al. 2017

Cureus

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“…Of the malignant masses, the most common was determined as GIST followed by liposarcoma and the most common of the benign masses was seen to be mesenteric cysts. GIST, which can originate from any part of the gastrointestinal tract, but primarily the stomach, are rarely seen masses with the potential to be malignant (10,12).…”

Section: The Process Of Diagnosis Of An Intra-mentioning

confidence: 99%

Diagnosis and Treatment Approaches for Intraabdominal Masses in Adults

Akkoca

2017

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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To evaluate patients who underwent surgery because of an intra-abdominal mass, in respect of symptoms, findings, diagnosis and treatment in accordance with information in literature. Material and Methods: A retrospective examination was made of patients who underwent surgery because of an intra-abdominal mass between May 2010 and May 2017. For each patient a record was made of age, gender, symptoms, findings, type of mass determined, diagnostic methods used, the organ or tissue of origin, whether or not preoperative biopsy was taken, dimension of the mass, benign or malignant nature of the mass, type of operation performed and pathological diagnosis. Results: Evaluation was made of 45 patients with an intra-abdominal mass. The patients comprised 18 (40%) males and 27 (60%) females with a mean age of 54.3 years (range, 19-86 years). The most common symptom was abdominal pain in 26 (57.8%) patients, and being able to feel the mass in the abdomen in 15 (33.4%). The intra-abdominal mass could be determined on palpation in 28 (62.2%) as a finding in the physical examination. USG was the most preferred imaging examination method in 36 (80%) patients, followed by CT in 28 (62.2%), MRI in 10 (22.2%) and PET-CT in 2 (4.4%). Preoperative endoscopy was applied to 27 (60%) patients and biopsy to 21 (46.7%). The long axis of the mass was mean 13cm (range, 4-50 cm). Treatment was applied as total excision of the mass in 29 (64.4%) patients, enbloc resection of the mass together with the bowel in 14 (31.1%), together with a distal pancreatectomy in 1 (2.2%) and together with a pancreaticoduodenectomy in 1 (2.2%). The pathology result was reported as benign in 15 (33.3%) patients and as malignant in 30 (66.7%). Of the benign masses, mesenteric cyst was determined most frequently in 5 (11.1%) patients and gastrointestinal stromal tumors (GIST) were determined as the most common malignant masses in 10 (22.2%) patients. Conclusion: Although intra-abdominal masses originate from different organs and have different clinical and histopathological properties, they are pathologies that require systematic evaluation in respect of diagnosis and treatment approaches.

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“…3 GISTs grow in three patterns: intramural, intraluminal, and exophytic. [4][5][6] We have previously reported 3 cases of endoscopically invisible medium-sized exophytic GISTs. 7 In this follow-up report, we describe our experience of another case of small exophytic GIST in the greater curvature of the gastric corpus detected by transabdominal ultra-sonography (TUS), for which we could trace the natural history retrospectively.…”

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confidence: 99%

Natural History of Exophytic Type Gastrointestinal Stromal Tumor: A Case Report

et al. 2019

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Gastrointestinal stromal tumor (GIST) is the most common submucosal tumor of the stomach. GISTs are often detected by esophagogastroduodenal endoscopy. We have previously reported on endoscopically invisible medium-sized exophytic type GISTs. We present here a case of small exophytic GIST detected by transabdominal ultrasonography (TUS) in which the natural history of the tumor could be traced retrospectively through incidental findings obtained during follow-up for intraductal papillary mucinous neoplasm by magnetic resonance of imaging or computed tomography over about 10 years. The tumor appeared 7 years before its detection, and the doubling time was calculated as 6.9 years. In conclusion, low-risk exophytic GIST was estimated to have taken at least about 7 years to reach a size detectable by TUS.

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A rare case of concomitant huge exophytic gastrointestinal stromal tumor of the stomach and Kasabach-Merritt phenomenon

Abstract: Since the characteristic of tumor in this case was hypervascularity with bleeding and necrotic lesions, coagulopathy was thought to be caused by the trapping of platelets within a large vasculized tumor mass.

Cited by 5 publications

References 17 publications

Gastrointestinal Stromal Tumors: Deception to the Eyesight

Gastrointestinal Stromal Tumors: Deception to the Eyesight

Diagnosis and Treatment Approaches for Intraabdominal Masses in Adults

Natural History of Exophytic Type Gastrointestinal Stromal Tumor: A Case Report

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