A Rare Case of Cutis Verticis Gyrata with Underlying Cerebriform Intradermal Nevus

Cerebriform intradermal nevus manifesting as cutis verticis gyrata

“…Finally, secondary CVG can be related to a variety of other disorders; which include hormonally driven diseases such as acromegaly, thyroid conditions and myxedema; hematologic diseases such as leukemia or amyloidosis; infectious agents such as syphilis or human immunodeficiency virus; inflammatory skin disorders such as eczema, psoriasis or Darier's disease; solitary neoplasms; and genodermatoses such as noonan syndrome, tuberous sclerosis complex, or neurofibromatosis. [6] e average number of skin folds with CVG in one study was six, though it may vary from two to as many as twenty folds. [7] e direction of the folds is usually anterior to posterior in vertex but may be transverse over the occipital region or sometime can be irregular.…”

Cutis Verticis Gyrata and epilepsy, is there a typical patient?

“…Numerous case reports have examined potential associations and causal factors related to Cutis Verticis Gyrata. For instance, a study documented a case in which secondary CVG developed in a 46-year-old female patient with Cerebriform Intradermal Nevus (11). Furthermore, an Italian article published in 2022 reported two cases of CVG occurring in patients with Noonan syndrome (12).…”

Cutis Verticis Gyrata – Klinika, Diagnostika, Gydymas

“…insulin-like growth factor 1, IGF-1) koncentracijos kraujyje nustatymas, sifilio, ŽIV serologija. Šie tyrimai gali padėti įtarti ar atmesti antrinį CVG sukeliančią patologiją: leukemiją, skydliaukės ligas, akromegaliją, sifilį ar su ŽIV susijusią lipodistrofiją [23,25,26]. Atliekant kompiuterinės tomografijos (KT) ar magnetinio rezonanso tomografijos (MRT) tyrimus, CVG atvejai gali būti identifikuoti ir atsitiktinai.…”