A Rare Case of Elizabethkingia meningoseptica Bacteremia After Liver Transplantation

Abstract

Patient: Female, 55-year-old Final Diagnosis: Bacteremia Symptoms: Fever Medication: — Clinical Procedure: — Specialty: Critical Care Medicine • Infectious Diseases Objective: Rare disease Background: Elizabethkingia meningoseptica is an emerging pathogen in hospital environments. Immunocompromised individuals have a high risk of infections caused by E. meningoseptica , especially after transplantation. E. meningoseptica is associated with prolonged hospital stays and high mortality. In addition , E. meningoseptica is commonly resistant to many antibiotics used for gram-negative bacterial infections . We introduce the first case of E. meningoseptica bacteremia in a recipient of a liver transplant in Vietnam. Case Report: A 55-year-old woman with end-stage liver disease due to biliary cirrhosis underwent living donor liver transplantation at the 108 Military Central Hospital. On day 3 after transplantation, the patient had an acute cellular rejection, and corticosteroid pulse therapy was used. On day 7 after transplantation, the patient had a fever and an increased white blood cell count and C-reactive protein level. Blood cultures were positive for E. meningoseptica . Intravenous levofloxacin was administered for 10 days. The patient showed an excellent treatment response to the antibiotic therapy and was discharged. Conclusions: E. meningoseptica , a multidrug-resistant gram-negative bacteria, can be considered an emerging pathogen in the hospital environment, especially in patients receiving organ transplants. Early recognition helps physicians to improve patient outcomes.

Whole-genome sequence and resistance determinants of four Elizabethkingia anophelis clinical isolates collected in Hanoi, Vietnam

“…have already been detected in several South-East Asian countries (Singapore, Malaysia, Indonesia, China, Thailand and Cambodia), but never in the Philippines, Brunei, Myanmar, Laos and Timor-Leste 68 . In Vietnam, Hoa and Hai recently reported the detection of an E. meningoseptica isolate in a patient who underwent liver transplantation at the 108 Military Central Hospital 72 , but this is the only previous report of an Elizabethkingia spp. infection in Vietnam, and genome sequencing was not carried out to confirm species identity.…”

A rare case of Elizabethkingia meningoseptica bacteremia followed by meningitis in post‐liver transplant patient

“…2,5 There were few cases reported in liver transplant patients. 1,6 We have a case of E. meningoseptica bacteremia followed by meningitis in a recipient of a liver transplant in a tertiary care hospital in Gujarat, India.…”

“…2,5 There were few cases reported in liver transplant patients. 1,6 We have a case of E. meningoseptica bacteremia followed by meningitis in a recipient of a liver transplant in a tertiary care hospital in Gujarat, India.Case report: A 50-year-old male patient with a history of decompensated chronic liver disease was admitted with acute-on-chronic liver failure with concomitant acute kidney injury (AKI). The patient's clinical course was characterized by intense medical management, involving broad-spectrum antibiotics, antifungal therapy, albumin administration, and vasoactive medications.…”

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A rare case of Elizabethkingia meningoseptica bacteremia followed by meningitis in post-liver transplant patientTo the Editor, Introduction: Elizabethkingia meningoseptica, a ubiquitous Gramnegative aerobic bacillus, is an emerging pathogen in the hospitalized patient. [1][2][3] Immunocompromised and transplant patients have higher risk to this infection. It has been isolated in the hospital environment in water supplies, disinfectants, sinks, taps, saline solutions used for flushing procedures, and medical devices, including feeding tubes, arterial catheters, and respirators.

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A Case of Community-Acquired Elizabethkingia meningoseptica

“…However, there have been an increasing number of reports of complicated infections with this bacterium worldwide. For example, there have been recent cases reported in Qatar, Vietnam, and other countries of E. meningoseptica as the causative organism affecting immunocompromised and pediatric patients, leading to prolonged and complicated hospitalizations [6,7,8,9]. With the increased risk of various complications caused by E. meningoseptica, heightened clinical awareness is warranted.…”