A Rare Case of Extramedullary-Intradural Hemangioblastoma in the Thoracic Spine

Abstract

STUDY DESIGN.: Case report. OBJECTIVE.: To present a rare case of extramedullary-intradural hemangioblastoma in the thoracic spine and to review the literature on this condition. SUMMARY OF BACKGROUND DATA.: Spinal hemangioblastoma is rare, and moreover, there is seldom purely extramedullary-intradural hemangioblastoma of the spinal cord and there are few reports on histopathological features of spinal hemangioblastoma. METHODS.: A 65-year-old Japanese woman presented with gait disturbance and numbness below the trunk that had gradually worsened, and finally she was unable to walk by herself. Physiologic and neurologic examinations at admission revealed severe transverse neurologic defects, with no sign of von Hippel-Lindau's disease. Radiologic methods showed an extramedullary-intradural mass at Th4-5. A diagnosis of extramedullary-intradural spinal tumor was done, total tumorectomy was performed with recapped laminoplasty. RESULTS.: The patient's neurologic condition gradually improved after the operation. The immunohistopathological findings revealed the diagnosis of hemangioblastoma. CONCLUSION.: A rare case of extramedullary-intradural spinal hemangioblastoma was reported. The immunohistopathological findings were helpful for making a final diagnosis.

Multiple Spinal Hemangioblastomas Complicated with Postoperative Remote Cerebellar Hemorrhage: Review of the Literature of Two Rare Entities

“…VHL disease or occurring sporadically (1). There have been <20 cases of spinal nerve hemangioblastomas described in the literature (2,12). We have reported here an exceptional case of multiple extramedullary hemangioblastomas.…”

Hemangioblastoma radicular extraforaminal de la raíz L4 derecha

“…Su localización más frecuente es a nivel de la fosa posterior y la médula espinal [2][3][4][7][8][9] . Dentro de los hemangioblastomas medulares, la localización más frecuente es la zona de entrada de la raíz dorsal con un crecimiento intramedular.…”

“…El diagnóstico por imagen de estas lesiones muestra en la RM potenciada en T1 un tumor hipointenso e hiperintenso en la RM potenciada en T2, con captación de contraste no homogénea [2][3][4][5][6][7][8][9] .…”

“…Taniguchi et al 7 refieren que el tratamiento ideal de los hemangioblastomas radiculares se basa en identificar el fascículo de origen y resecarlo junto con el tumor, evitando así recurrencias.…”

Multi-modality Management of an Intradural-Extramedullary Hemangioblastoma: A Case Report

“…1 Less than 20% of hemangioblastomas are located in the spinal cord; 1,8 these lesions are typically intradural, intramedullary, and rarely extramedullary. 7 Spinal hemangioblastoma may present with a wide variety of clinical symptoms, ranging from mild neurological symptoms to paralysis. 1 A 79-year-old gentleman with a four-month history of progressively deteriorating tetraparesis was transferred to our institution.…”