A Rare Case of Herpes Zoster in an Adult Patient Recovered From Symptomatic Reinfection of COVID-19

Abstract

In coronavirus disease 2019 (COVID-19) patients, various dermatological conditions have been observed. Varicella zoster virus (VZV) and herpes simplex virus must be ruled out before considering vesicular exanthems linked to COVID-19. The immunological status of the host has an impact on the natural history of herpes zoster (HZ). Age is a major risk factor for most of the cases of HZ. Reactivation of VZV can be triggered by iatrogenic immunosuppression or disease-related immunocompromised state or age-related immunosenescence. Rarely, dermatological symptoms have been reported in recovered COVID-19 patients. We hereby present a rare case of HZ in a recovered patient from symptomatic reinfection of COVID-19.

Varicella-Zoster virus reactivation following severe acute respiratory syndrome coronavirus 2 vaccination or infection: New insights

“…A total of 314 studies were identified. After applying the inclusion and exclusion criteria, 55 studies [11] , [12] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] , [26] , [27] , [28] , [29] , [30] , [31] , [32] , [33] , [34] , [35] , [36] , [37] , [38] , [39] , [40] , [41] , [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] of VZV manifestations in subjects with SARS-CoV-2 vaccinations or COVID-19 disease were deemed eligible for inclusion. A flow diagram of the selection of the studies is presented in Fig.…”

Characteristics of herpes zoster infection in patients with COVID‐19: a systematic scoping review

“…A total of 19 articles with three observational studies and 16 case reports or series were included in the review. 6,[13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30] Description of included studies Table 1 describes the main characteristics of three observational studies from the scoping review. Giavedoni et al conducted a retrospective analysis of COVID-19 skin lesions in order to characterize the clinical patterns of the lesions.…”

Case of atypical disseminated herpes zoster in a patient with COVID‐19: A diagnostic challenge in COVID era

“…7 A few cases of COVID-associated HZ were reported during the current pandemic which unlike to our case, none of them pose a diagnostic challenge. [8][9][10][11] The majority of these cases including ours belonged to the age group above 50 years. 9 However, most of those patients developed cutaneous lesions up to 1 week after the onset of COVID symptoms, [12][13][14] which was not congruent with the course of disease in our patient.…”

“…A few cases of COVID‐associated HZ were reported during the current pandemic which unlike to our case, none of them pose a diagnostic challenge. 8 , 9 , 10 , 11 …”