A rare case of idiopathic thrombocytopenia in association with an ovarian teratoma in pregnancy

Abstract

Summary: Thrombocytopenia complicates 6 -7% of pregnancies. We present the case of a 26-year-old patient who presented with severe thrombocytopenia associated with an ovarian teratoma in the second trimester of pregnancy.

Ovarian teratoma: yet another cause of immune thrombocytopenia

“…There is one case of ITP in association with ovarian teratoma described in the literature and was concomitant with pregnancy. 5 The characteristics of this case and our case are presented in Table 1 . Other cases of ITP were described with extragonadal germ cell tumors where all had embryonal cancers with mediastinal masses.…”

“…Thrombocytopenia was the hematologic disorder found in association with the ovarian teratoma. 5 Nevertheless other hematologic abnormalities that can be seen may include myelodysplasia, idiopathic thrombocytosis, acute lymphocytic leukemia, or acute myeloid leukemia. 6 – 8 …”

“…To date, one case was reported in literature of ITP associated with an ovarian teratoma. 5 The mechanism of association is still intriguing.…”