A rare case of infectious colitis

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for numerous infectious processes. Gastrointestinal tract involvement is rather rare and only a handful of cases of MRSA colitis have been reported in North America. We present a case of MRSA colitis in an adult without apparent risk factors. Abdominal computed tomography (CT) showed thickening of the sigmoid colon, indicative of colitis, and empiric therapy with ciprofloxacin and metronidazole was started. Initial work-up for infection—including blood and stool cultures, and stool Clostridium difficile toxin assay—was negative. The patient’s clinical status improved but his diarrhea did not abate. Repetition of stool culture demonstrated luxuriant growth of MRSA sensitive to vancomycin. Oral vancomycin was administered and the patient’s symptoms promptly ceased.

Methicillin-resistantStaphylococcus aureus: a controversial food-borne pathogen

“…A French study on foods incriminated in SFP outbreaks revealed two MRSA strains of the 33 strains tested (K erouanton et al 2007); compared to human clinical isolates, the SFP outbreak strains were more susceptible to antibiotics (except for two SFP outbreak strains that were resistant to methicillin). More recently, a rare case of MRSA colitis in an adult (without any apparent predisposing medical condition) has been reported in the United States (Kalakonda et al 2015). This was the sixth reported case of MRSA colitis in the literature since 1993 (Kalakonda et al 2015).…”

“…More recently, a rare case of MRSA colitis in an adult (without any apparent predisposing medical condition) has been reported in the United States (Kalakonda et al . ). This was the sixth reported case of MRSA colitis in the literature since 1993 (Kalakonda et al .…”

“…This was the sixth reported case of MRSA colitis in the literature since 1993 (Kalakonda et al . ). Boyce and Havill () reported 11 cases of MRSA nosocomial‐associated diarrhoea in the United States; the isolates produced SE A ( n = 2), A and B ( n = 6), or D ( n = 3), whereas the MRSA counts in the stools of affected patients exceeded 1·0 × 10 8 CFU per g.…”

“…More recently, a rare case of MRSA colitis in an adult (without any apparent predisposing medical condition) has been reported in the United States (Kalakonda et al 2015). This was the sixth reported case of MRSA colitis in the literature since 1993 (Kalakonda et al 2015). Boyce and Havill (2005) reported 11 cases of MRSA nosocomial-associated diarrhoea in the United States; the isolates produced SE A (n = 2), A and B (n = 6), or D (n = 3), whereas the MRSA counts in the stools of affected patients exceeded 1Á0 9 10 8 CFU per g.…”

Early detection of ulcerative colitis-associated colorectal cancer

“…Although several recent reports have indicated a slight decline in CACC incidence in IBD patients [ 7 , 8 ], which might be attributed to the widespread use of 5-aminosalicylic acid and immunosuppressive drugs [ 9 , 10 ], as well as to widespread endoscopic screening and early coloproctectomy, current guidelines continue to recommend a regular surveillance for early detection [ 11 ]. Moreover, because of worse prognosis and higher mortality in CACC than in sporadic CRC [ 12 ], early CACC detection is crucial. Colonoscopy is primarily recommended for surveillance; however, newer technologies and approaches, such as molecular biomarkers in different biosamples, have emerged and the best approach and technique for surveillance remain under debate.…”