A rare case of invasive vaginal carcinoma associated with vaginal prolapse

Abstract

Careful preoperative histological evaluation of cervix in cases of uterine prolapse and postoperative cytologic and colposcopic follow-up of the vagina after hysterectomies are important because possible association with cervical carcinoma and occurrence of late vaginal cancer. Surgery and radiotherapy were effectively combined in this case that remains with no recurrence after 2 years follow-up.

Squamous cell carcinoma of the vagina: natural history, treatment modalities and prognostic factors

“…This malignancy has also been found in patients with vaginal or utero-vaginal prolapse [23][24][25]. Anecdotal cases have been described in women who had undergone vaginoplasty for vaginal agenesis due to Rokitansky-Kuster-Hauser syndrome [26][27][28].…”

Using a pessary during radiotherapy in reducible pelvic organ prolapse and vaginal cancer: a case report and review of the literature

“…Vaginal trauma, chronic irritation, and inflammation of the vaginal mucosa can cause primary vaginal cancer in patients with POP [3]. However, a combination of POP and primary vaginal or cervical cancer is an extremely rare entity [4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19].…”

Carcinoma of Vagina in Utero-Vaginal Prolapse: A Rare Presentation

“…Primary vaginal carcinoma is rare and comprises only one to two percent of all gynecologic malignancies 1 with its incidence peak during the sixth decade. 2 The development of carcinoma of vagina in the ulcerated part of the uterovaginal prolapse is a rare entity described in the English literature. Herein, we present a case of an early stage of vaginal carcinoma developed in the long standing uterovaginal prolapse with review of the related literature.…”