A rare case of juvenile acute non-proliferative glomerulonephritis with a 6-year follow-up experience

Abstract

Juvenile acute non-proliferative glomerulonephritis (JANG) is a relatively new clinico-pathological entity established in 2000. A PubMed search revealed only two published reports encompassing 14 cases of JANG. It is distinguished from acute post-streptococcal glomerulonephritis by the presence of normal serum complement and the absence of diffuse proliferation of mesangial cells in the glomeruli. We report a case of a 4-year-old child that presented with a clinical scenario and renal biopsy findings consistent with JANG. She responded well to treatment with high-dose methylprednisolone for 3 days, followed by gradual taper with oral prednisone. She was monitored closely for a period of 6 years and continues to do well with normal renal parameters and without any medications.