A Rare Case of Large Uterine Myoma in an Antenatal Women with Situs Inversus: A Case Report

Abstract

Leiomyomas or fibroids are the most common benign tumor of uterus and it often increases in size during pregnancy. Its incidence in pregnancy is approximately 1.5-2% and is associated with increased risk of complication during pregnancy including abortions, preterm labor, red degeneration, malpresentations, increased cesarean section rates, postpartum hemorrhage. We hereby, discuss a case of large multi-lobed uterine fibroid complicating the second trimester of pregnancy. Our patient presented with a large leiomyoma of approximately 28 × 30 cm size at 28 weeks of gestation with acute red degeneration of fibroid with intracapsular and intra-peritoneal bleed. Life saving subtotal hysterectomy was done and around 1.5-2 liters of blood was drained out from the abdominal cavity. The total weight of uterus with fibroid was around 15 kg and benign leiomyoma was confirmed on histopathological examination.

A Rare Case of Large Uterine Fibroid in Pregnancy

“…A variety of factors such as epigenetic or genetic mechanism, disorganization of extracellular matrix, growth factors have shown interaction with pathogenesis of growing fibroid. As far as management is considered, conservative with antiinflammatory therapy is considered as gold standard, and the surgery is generally avoided during pregnancy because of the risks of hysterectomy secondary to severe haemorrhage, pregnancy injury, and pregnancy loss [4].…”