A Rare Case of Left Main Coronary Stenosis and Neutropenia Treated with G-CSF Prior to CABG

Abstract

A 70-year-old male known with myelodysplastic syndrome (MDS) was admitted with effort angina and fever, which developed into unstable angina. On coronary angiography a critical stenosis of the left main coronary artery and 75% stenosis of the right coronary artery were found. On complete blood count the number of leukocytes was 1600/µl. We administered granulocyte colony-stimulating factor (G-CSF) twice daily to increase the number of leucocytes. After two days the number of leukocytes had increased to 8700/µl. The patient was admitted to the operating room and off-pump coronary artery bypass grafting was performed successfully.

Minimally invasive mitral valve repair via right mini-thoracotomy in patient with myelodysplastic syndrome

“…Cardiac surgery for MDS patients is rare, with only 13 cases reported thus far (Table 1 ). Most of those were performed due coronary artery bypass grafting [ 7 – 9 ] or aortic valve replacement [ 10 – 14 ] through a median sternotomy. Due to the variety of disease presentations, management and outcomes in previous reports differ.…”

Mitral and Tricuspid Valvuloplasty in a Patient With Myel-Odysplastic Syndrome

“…U većine je zbog bolesti koronarnih arterija potrebno aortokoronarno premoštenje. [6][7][8] Samo je nekoliko pojedinačnih prikaza bolesnika s mijelodisplastičnim sindromom kod kojih je učinjen kirurški zahvat rekonstrukcije aortalne ili mitralne valvule, jer opsežan zahvat često dovodi do krvarenja te infektivnih komplikacija. [9][10][11][12][13][14][15][16][17][18][19] Dosad je u literaturi opisan samo jedan prikaz istodobnog izvođenja mitralne i trikuspidalne valvuloplastike.…”

“…Kardiokirurški zahvati u bolesnika s MDS-om rijetki su, uglavnom je riječ o aortokoronarnom premoštenju ili zamjeni aortalne ili mitralne valvule. [6][7][8][9][10][11][12][13][14][15][16][17][18] Operativni je postupak kompleksan. Ako bolesnik i preživi zahvat, postoji mogućnost postoperativnih komplikacija, kao i pogoršanja MDS-a.…”