A rare case of malignant meningitis from a likely bronchogenic melanoma primary cancer

Abstract

Malignant meningitis is a rare condition with varied clinical presentations, often mimicking other neurological conditions. Here we report a rare case of malignant meningitis from primary bronchogenic melanoma. The patient initially presented with vomiting and headache. Over the next 12 days she developed rapidly progressive neurology: losing mental faculties, vision, hearing and limb power. Lumbar puncture results revealed malignant cells. Computer tomography of the chest found an endobronchial lesion which was later biopsied and histology revealed a melanoma. This condition is very rare and diagnosis was difficult. We discuss ideas to help expedite diagnosis and management of such cases in the future.

A case of mistaken identity: An unusual presentation of neoplastic meningitis and a reminder of the hallmark features

“…Previous case reports have detailed a range of clinical features including headache, altered mental status, and visual disturbances, often requiring repeated review prior to the eventual correct diagnosis of neoplastic meningitis being made. [2][3][4] This case highlights another manifestation, namely dizziness, which was initially attributed to a diagnosis of benign paroxysmal positional vertigo (BPPV).…”