A rare case of metastatic lung cancer to the bladder

Karle, William E.; Barazani, Yagil; Tareen, Basir

doi:10.5489/cuaj.307

Cited by 4 publications

(4 citation statements)

References 4 publications

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“…Metastatic lesions to the bladder can also be found incidentally, as in a case report from 2012 in which pulmonary metastasis to the bladder was found prior to clinical symptoms. 3 While our patient presented with typical symptoms seen in those with bladder tumors, this is the first case in which the patient had no previous diagnosis of lung cancer prior to identification of a metastatic bladder mass of pulmonary origin. Diagnosis and suspicion for lung cancer was more difficult given the patient's previous history of prostate cancer and pelvic radiation.…”

Section: Discussionmentioning

confidence: 64%

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A case of metastatic lung adenocarcinoma of the bladder in a patient with no documented history of lung cancer

Azaiza,

Yallapragada,

Siegert

et al. 2023

Urology Case Reports

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Section: Discussionmentioning

confidence: 64%

“…It may be difficult to diagnose and tend to have a more unfavorable outcome that primary bladder cancers. 3 , 5 Our patient unfortunately only lived for roughly 3 months following his diagnosis. A history of lung adenocarcinoma is not always necessary in order to find metastasis to the bladder.…”

Section: Discussionmentioning

confidence: 91%

A case of metastatic lung adenocarcinoma of the bladder in a patient with no documented history of lung cancer

Azaiza,

Yallapragada,

Siegert

et al. 2023

Urology Case Reports

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“…Furthermore, in a retrospective study from 282 cases of secondary bladder neoplasms, only one case (0.4%) originating from lung adenocarcinoma was identified (5). Among the six cases reported in the literature, four cases presented clinical data, including age, gender and clinical symptoms (4,(7)(8)(9). The age range of the subjects was 40-81 years, with a mean age of 66 years.…”

Section: Discussionmentioning

confidence: 99%

“…Out of these previous studies, two patients presented with gross hematuria, one presented with pain and bilateral hydronephrosis, and one was initially referred to the neurosurgical clinic for left carpal tunnel syndrome. However, both patients were confirmed to have a history of primary lung cancer following careful physical examination (8,9). In the current case, the patient presented with a gross hematuria >2 years following diagnosis of the primary lung adenocarcinoma.…”

Section: Discussionmentioning

confidence: 99%

Metastatic lung adenocarcinoma to the bladder: A case report

Liu

et al. 2015

Oncology Letters

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Abstract. Urothelial cancer is the most frequently diagnosed type of malignant tumor in the bladder, of which primary adenocarcinoma accounts for a small percentage. Secondary malignancies, in particular metastatic adenocarcinoma from the lung, are exceedingly rare, with only six cases previously reported in the literature. The present study describes the case of a 71-year-old Chinese male patient with known lung cancer for >2 years, who was diagnosed with metastatic adenocarcinoma to the bladder. The histopathological characteristics and immunohistochemical features of the patient are reported. It was proposed that pathologists should consider the possibility of metastatic adenocarcinoma from the lung, rather than assume a diagnosis of primary adenocarcinoma of the bladder or direct invasion of adenocarcinoma from the surrounding organs. Furthermore, it is essential to determine the medical history of each patient and observe the immunohistochemical features of all tumors prior to diagnosis. IntroductionBladder cancer is the fifth most common type of malignant tumor. Among bladder malignancies, urothelial carcinomas are the most frequent histological type, of which adenocarcinoma, squamous cell cancer and small-cell cancer account for small percentages (1,2). Primary adenocarcinomas were reported to account for 0.5-2% of primary bladder epithelial malignancies; these malignancies most commonly arise in the urachus (3).In addition, secondary adenocarcinomas may also occur as a result of direct invasion from the surrounding organs, including prostate, colorectal and cervical sites (3). Furthermore, metastatic spread may occur via lymphogenous or hematogenous routes (4). However, the bladder is not a favored site for tumor metastases; in particular, adenocarcinoma from the lung is exceptionally rare (5). The present study describes a case of metastatic adenocarcinoma from the lung to the bladder and reports the histopathological characteristics and immunohistochemical features of the patient. The aim of the present study was to emphasize the importance of considering of metastatic adenocarcinoma from the lung as a possible diagnosis, in addition to primary adenocarcinoma and direct invasion of adenocarcinoma from the immediate surrounding organs. Case reportA 71-year-old Chinese male with known lung cancer for >2 years was referred to the People's Liberation Army 205 Hospital (Jinzhou, China) due to a gross hematuria, which had persisted for 5 days. This initial diagnosis of lung adenocarcinoma occurred >2 years previously, when the patient was admitted to a local hospital due to a cough and expectoration. Following the initial admission to hospital, a thoracic computed tomography (CT) revealed a 3x2x2 cm mass in the lower lobe of the patient's left lung; consequently, a needle biopsy was performed and the patient was diagnosed with adenocarcinoma of the lung (histological sections were not available for review). The patient elected not to undergo any therapy, including surgical resection, chemical therapy or radi...

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