A Rare Case of Multiple Spindle Cell Lipomas

Kim, Dae Hong; Lee, Young Bok; Kim, Jin Woo; Yu, Dong

doi:10.5021/ad.2015.27.4.472

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“…The age range is from 40 to 70 years (mean = 57, median = 55) with a substantial number of cases having an earlier onset, developing as significant lesions over a period of time (Enzinger and Harvey 1995;Angervall et al 1976;Fletcher and Martin-Bates 1987;Shmookler and Enzinger 1981;Azzopardi et al 1983). Rarely, these tumors have been reported as multiple lesions, including cases with a familial occurrence (Fanburg-Smith et al 1998;Kim et al 2015).…”

Section: Clinical Featuresmentioning

confidence: 99%

Spindle Cell Lipoma/Pleomorphic Lipoma

Rekhi

2019

Encyclopedia of Pathology

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Spindle cell/pleomorphic lipoma, together represent a morphological continuum, mostly occur in the neck and upper trunk of older males and are histopathologically characterized by relatively bland spindle cells, admixed with mature adipose tissue, along with variable myxoid stroma, ropey collagen, and pleomorphic, multinucleate giant cells, the latter feature pronounced in the pleomorphic lipoma. These tumors are invariably immunoreactive for CD34.

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