Purpose
This retrospective study aimed to investigate the clinical features and morphological characteristics of myocardial bridging involving the left circumflex artery and its branches using coronary computed tomography angiography.
Methods
We enrolled 23 patients (mean age: 55.65 ± 13.28 years) with myocardial bridging of the left circumflex artery between January 1, 2014 and July 31, 2020. All patients underwent coronary computed tomography angiography and electrocardiography. The morphology, clinical findings, and coronary computed tomography angiography -derived fractional flow reserve were compared for patients with myocardial bridging of a single left circumflex artery (n = 23), right coronary artery (n = 10), and left anterior descending artery (n = 23).
Results
Myocardial bridging of the left circumflex artery were more commonly superficial (superficial myocardial bridging: 22 vs. deep myocardial bridging: 1) while bridging in the left anterior descending artery was mostly located in the middle segment (91%, 21/23), and bridging in the left circumflex artery was mostly located on the distal-segment or obtuse marginal branch (87%, 20/23). The 95% confidence interval of myocardial bridging thickness, myocardial bridging length, arterial diameter in systole and diastole period of the myocardial bridging of the proximal segment was: 0.24 (0.05, 0.43), 2.88 (2.32, 3.42), 1.67 (1.47, 1.87), and 1.74 (1.54, 1.95), respectively. 95% confidence interval of computed tomography-derived fractional flow reserve in the proximal and distal segments of bridging were 0.96 (0.96, 0.97) and 0.93 (0.92, 0.94), respectively. All heart dominance showed right coronary dominance (73.91%, 17/23) or co-dominance (26.09%, 6/23).
Conclusions
All patients with bridging segments in the left circumflex artery have right coronary dominant or co-dominant hearts. Bridging of the left circumflex artery is mostly long and located in the distal segment. Computed tomography-derived fractional flow reserve showed a low value in diagnosing myocardial ischemia resulting from myocardial bridging of the left circumflex artery.