A Rare Case of Non-Prosthetic Aortic Valve Infectious Endocarditis Caused by Achromobacter xylosoxidans

Castro, Ricardo Lessa de; Lima, Neiberg de Alcantara; Lino, Danielli Oliveira da Costa; Melgar, Thomas

doi:10.12659/ajcr.923031

Cited by 10 publications

(14 citation statements)

References 22 publications

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“…In this paper we describe a case of native aortic endocarditis caused by A. xylosoxidans in an immunocompromised patient successfully treated with cefiderocol based therapy. To our knowledge, only 16 other cases of A. xylosoxidans endocarditis involving the aortic valve have been described in the literature so far [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ] ( Table 2 ), and none treated with cefiderocol.…”

Section: Discussionmentioning

confidence: 99%

Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

et al. 2022

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Achromobacter xylosoxidans is a Gram-negative aerobic opportunistic bacterium, belonging to the order of Burkholderiales, that can cause infections of virtually all body districts in patients with underlying diseases. However, A. xylosoxidans has rarely been associated with infective endocarditis. The treatment of A. xylosoxidans infections is complicated by both intrinsic and acquired resistance. Here we report on a case of aortic endocarditis by A. xylosoxidans in a Non-Hodgkin lymphoma patient treated with a combination of cefiderocol and other antibiotics, and summarize the available literature.

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Section: Discussionmentioning

confidence: 99%

Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

et al. 2022

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“…In the reviewed articles, the most common feature among the patients is an underlying malignancy. Infective endocarditis typically occurs in patients with valve replacement, although one case of infective endocarditis was reported in a healthy immunocompetent patient with a native valve [ 8 ]. One case report described a patient with pulmonary tuberculosis and Achromobacter xylosoxidans bacteremia, which was complicated by septic shock and death [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Achromobacter xylosoxidans Bacteremia in a Liver Transplant Patient: A Case Report and Literature Review

Barakat¹,

Sajid²

2022

Cureus

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Since the first isolation of Achromobacter xylosoxidans, it has been increasingly recognized as an opportunistic pathogen. It is an aerobic Gram-negative bacillus mainly found in aquatic environments. It has been reported to cause nosocomial infections, especially in immunocompromised patients. This organism has a unique susceptibility to antimicrobials, being resistant to most commonly used cephalosporins and aminoglycosides, with susceptibility to piperacillin/tazobactam and most carbapenems. In this case, we report a case of a 60-year-old female with a history of liver transplantation, who developed nosocomial Achromobacter xylosoxidans bacteremia complicated by septic shock, multi-organ failure, and death.

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“…Инфекции дыхательных путей [65][66][67] Инфекции мочевыводящих путей, включая абсцессы почек и паранефральные абсцессы [68][69][70] Инфекции кровотока [71,72] Менингиты, абсцесс мозга [73,74] Абсцессы печени [5] Панкреатиты [75] Раневые инфекции, поражения кожи и подкожной клетчатки [75][76][77] Девайсассоциированные инфекции [78] Эндокардиты [79][80][81] Медиастиниты [4] Поражения ЛОРорганов (синуситы, отиты) [82,83] Поражения органа зрения (эндофтальмиты, кератиты) [84,85] Перитониты, абсцессы брюшной полости и забрюшин ного пространства [86,87] Остеомиелит…”

Section: патология ссылкаunclassified

Enigmatic Achromobacter

Chebotar

Bocharova

2022

CMAC

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This review aims to describe the microbiological characteristics, resistant features and pathogenic potential of Achromobacter spp. Achromobacter as an opportunistic pathogen can cause severe and even fatal infections. The current knowledge about molecular basis of clinically significant traits of Achromobacter spp. was critically analyzed. The understanding of pathogenicity factors of Achromobacter spp. are largely based on predictive analysis and the role of the most factors was not confirmed by in vivo and in vitro studies. Achromobacter spp. are intrinsically resistant to many groups of antibiotics and can rapidly acquire an adaptive antibiotic resistance. Only three antibiotics (meropenem, piperacillin/tazobactam, and trimethoprim/sulfamethoxazole) have the established breakpoints for Achromobacter spp. There is an unmet need to develop available and accurate methods for species identification of Achromobacter spp.

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A Rare Case of Non-Prosthetic Aortic Valve Infectious Endocarditis Caused by Achromobacter xylosoxidans

Cited by 10 publications

References 22 publications

Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

Successful Treatment of Aortic Endocarditis by Achromobacter xylosoxidans with Cefiderocol Combination Therapy in a Non-Hodgkin Lymphoma Patient: Case Report and Literature Review

Achromobacter xylosoxidans Bacteremia in a Liver Transplant Patient: A Case Report and Literature Review

Enigmatic Achromobacter

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