A rare case of pleural effusion due to Prevotella dentalis

Cobo, Fernando; Calatrava, Elizabeth; Rodríguez‐Grangér, Javier; Sampedro, Antonio; Aliaga-Martínez, Luis; Navarro-Marí, José María

doi:10.1016/j.anaerobe.2018.09.004

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…The most compelling evidence for "occult" anaerobes in empyema fluid is detection of bacterial DNA or RNA using massive parallel sequencing. This approach identified anaerobic bacteria in 70% patients with empyema and no known etiology (Cobo et al, 2018).…”

Section: Discussionmentioning

confidence: 99%

Identification of Microbiome Etiology Associated With Drug Resistance in Pleural Empyema

Chen

Cheng

Cai

et al. 2021

Front. Cell. Infect. Microbiol.

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Identification of the offending organism and appropriate antimicrobial therapy are crucial for treating empyema. Diagnosis of empyema is largely obscured by the conventional bacterial cultivation and PCR process that has relatively low sensitivity, leading to limited understanding of the etiopathogenesis, microbiology, and role of antibiotics in the pleural cavity. To expand our understanding of its pathophysiology, we have carried out a metagenomic snapshot of the pleural effusion from 45 empyema patients by Illumina sequencing platform to assess its taxonomic, and antibiotic resistome structure. Our results showed that the variation of microbiota in the pleural effusion is generally stratified, not continuous. There are two distinct microbiome clusters observed in the forty-five samples: HA-SA type and LA-SA type. The categorization is mostly driven by species composition: HA-SA type is marked by Staphylococcus aureus as the core species, with other enriched 6 bacteria and 3 fungi, forming a low diversity and highly stable microbial community; whereas the LA-SA type has a more diverse microbial community with a distinct set of bacterial species that are assumed to be the oral origin. The microbial community does not shape the dominant antibiotic resistance classes which were common in the two types, while the increase of microbial diversity was correlated with the increase in antibiotic resistance genes. The existence of well-balanced microbial symbiotic states might respond differently to pathogen colonization and drug intake. This study provides a deeper understanding of the pathobiology of pleural empyema and suggests that potential resistance genes may hinder the antimicrobial therapy of empyema.

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Section: Discussionmentioning

confidence: 99%

Identification of Microbiome Etiology Associated With Drug Resistance in Pleural Empyema

Chen

Cheng

Cai

et al. 2021

Front. Cell. Infect. Microbiol.

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“…Parvimonas micra, previously known as Peptostreptococcus micros or Micromonas micros [4], is a non-spore forming, strictly anaerobic, slow-growing, occurring in pairs and short chains, Gram-positive coccus, belonging to commensal flora of oral cavity, gastrointestinal and genital tracts. It was deemed to cause bacteremia [5,6], endocarditis [7], pleural effusion [8], septic pulmonary embolism [9], bone [10][11][12][13] and cerebral infections, mainly in patients which have undergone dental medical procedures (DMP) [11,[12][13][14][15][16][17][18][19] or with suboptimal oral hygiene [20][21][22][23]. Few data about clinical features and management of P. micra infections after medical procedures, above all in cases of infections after non-dental medical procedures (NDMP), are reported in literature [8,19,22,[24][25][26][27][28] In our case, patient showed no dental alterations nor periodontal disease and P. micra probably translocated into the bloodstream due to an imperceptible mucosal injury during endoscopy.…”

Section: Introductionmentioning

confidence: 99%

Parvimonas micra bacteremia following endoscopic retrograde cholangiopancreatography: A new route of infection

et al. 2018

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Parvimonas micra is an anaerobic, Gram-positive coccus belonging to oral, gastrointestinal and genital flora, rarely causing infections in humans. It was mainly deemed to cause bacteremia, septic bone and cerebral infections in patients which have undergone dental procedures or with suboptimal dental hygiene. We report the first case of Parvimonas micra bacteremia following endoscopic retrograde colangiopancreatography performed due to choledocholithiasis in a patient with good oral health. Identification of P. micra was finally performed by Matrix-assisted laser desorption ionization-time of flight mass spectrometry (VITEK MS system, bioMérieux, Marcy l'Étoile, France). All cases reported in english language of Parvimonas micra infections after medical procedure are reviewed in order to alert clinicians about new possible routes of infection of this emerging pathogen.

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“…They are usually associated with oral infections, but it can be also observed in some other infections such as skin and soft tissue, and pleuropulmonary infections. Until now, there are only few reports on pleural infection published in the literature caused by Prevotella species and obtained in pure culture [ 1 - 7 ]. We here present two additional and uncommon cases of pleural infection caused by Prevotella species and a review of the cases previously published.…”

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confidence: 99%

Two rare cases of pleural infection due to Prevotella species

Cobo¹,

Lara-Oya²,

Correa³

et al. 2022

Rev Esp Quimioter

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replacement was initiated. A hormonal study was performed showing increased levels of TSH (31.59), antibodies antiperoxidase (>1000 UI/mL) and decreased levels of thyroxine (<0.28 ng/dL). Moreover, the antinuclear antibodies were positives. The patient was diagnosed of systemic lupus erythematosus and myxedematous coma. Later, a chest ultrasound revealed a left pleural effusion; drainage was then performed.Both pleural fluids were sent to the microbiology laboratory for culture. The two samples were inoculated onto both aerobic and anaerobic blood agar (Becton Dickinson), chocolate agar (Becton Dickinson), and thioglycolate broth (Becton Dickinson), incubating all media at 37º C for 5 days. Gram staining of both fluids exhibited abundant Gramnegative rods. On the second day of incubation, numerous Two rare cases of pleural infection due to Prevotella species

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A rare case of pleural effusion due to Prevotella dentalis

Cited by 6 publications

References 10 publications

Identification of Microbiome Etiology Associated With Drug Resistance in Pleural Empyema

Identification of Microbiome Etiology Associated With Drug Resistance in Pleural Empyema

Parvimonas micra bacteremia following endoscopic retrograde cholangiopancreatography: A new route of infection

Two rare cases of pleural infection due to Prevotella species

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