A rare case of pregnancy with restrictive cardiomyopathy

Nayak, U Ashwini; Shekhar, Saketh P; Sundari, N

doi:10.4103/2211-4122.183763

Cited by 4 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Restrictive cardiomyopathies are rare and heterogeneous conditions characterized by a preserved or slightly reduced LV systolic function and severe diastolic dysfunction [ 90 ]. The increase in blood volume during pregnancy might theoretically increase the risk of pulmonary edema in patients with restrictive physiology, but the few case reports available seem not to support this hypothesis [ 91 , 92 ].…”

Section: Influence Of Maternal Cardiomyopathies On Pregnancymentioning

confidence: 99%

Disease features and management of cardiomyopathies in women

Aimo,

Morfino,

Arzilli

et al. 2024

Heart Fail Rev

View full text Add to dashboard Cite

Over the last years, there has been a growing interest in the clinical manifestations and outcomes of cardiomyopathies in women. Peripartum cardiomyopathy is the only women-specific cardiomyopathy. In cardiomyopathies with X-linked transmission, women are not simply healthy carriers of the disorder, but can show a wide spectrum of clinical manifestations ranging from mild to severe manifestations because of heterogeneous patterns of X-chromosome inactivation. In mitochondrial disorders with a matrilinear transmission, cardiomyopathy is part of a systemic disorder affecting both men and women. Even some inherited cardiomyopathies with autosomal transmission display phenotypic and prognostic differences between men and women. Notably, female hormones seem to exert a protective role in hypertrophic cardiomyopathy (HCM) and variant transthyretin amyloidosis until the menopausal period. Women with cardiomyopathies holding high-risk features should be referred to a third-level center and evaluated on an individual basis. Cardiomyopathies can have a detrimental impact on pregnancy and childbirth because of the associated hemodynamic derangements. Genetic counselling and a tailored cardiological evaluation are essential to evaluate the likelihood of transmitting the disease to the children and the possibility of a prenatal or early post-natal diagnosis, as well as to estimate the risk associated with pregnancy and delivery, and the optimal management strategies.

show abstract

Section: Influence Of Maternal Cardiomyopathies On Pregnancymentioning

confidence: 99%

Disease features and management of cardiomyopathies in women

Aimo,

Morfino,

Arzilli

et al. 2024

Heart Fail Rev

View full text Add to dashboard Cite

show abstract

“…Pregnancy in patients with restrictive cardiomyopathy is rare. 64 During pregnancy, there is increased stroke volume leading to increased load on restrictive myocardium. Additionally, with an increased heart rate from baseline, there are reduced diastolic filling times which may exacerbate HF in patients with restrictive disease.…”

Section: Pregnancy In Other Cardiomyopathiesmentioning

confidence: 99%

Intersection of Heart Failure and Pregnancy: Beyond Peripartum Cardiomyopathy

DeFilippis

Haythe

Walsh

et al. 2021

Circ: Heart Failure

View full text Add to dashboard Cite

Heart failure (HF) is a leading cause of morbidity and mortality in pregnant women in the United States. Although peripartum cardiomyopathy is the most common diagnosis for pregnant women with HF, women with preexisting cardiomyopathies and systolic dysfunction are also at risk as the hemodynamic demands of pregnancy can lead to decompensation, arrhythmia, and rarely death. The differential diagnosis of HF in pregnancy is broad and includes Takotsubo or stress cardiomyopathy, exacerbation of a preexisting cardiomyopathy, such as familial cardiomyopathy, hypertrophic cardiomyopathy, arrhythmogenic right ventricular cardiomyopathy, or left ventricular noncompaction. This review will explore the implications of pregnancy in women with preexisting cardiomyopathies and de novo HF, risk assessment and preconception planning, decisions about contraception, the safety of HF medications and implantable cardioverter-defibrillators during pregnancy, pregnancy in women with left ventricular assist devices and following heart transplantation.

show abstract

The challenge of cardiomyopathies and heart failure in pregnancy

Limongelli

Rubino

Esposito

et al. 2018

Current Opinion in Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

Purpose of review To discuss the risk preexisting or new onset cardiomyopathy/heart failure (CMP/heart failure) in pregnant woman, and recent insights regarding their management and therapy. Recent findings Recent data from the European Registry on Pregnancy and Heart disease of the European Society of Cardiology (ROPAC) suggest that, after an adequate prepregnancy evaluation in specialized centres, the vast majority of pregnancies are safe for both mother and foetus. A tailored approach is required according to cardiac phenotype (i.e. type of cardiomyopathy), clinical and functional status, and new potential treatments (i.e. bromocriptine in patients with peripartum cardiomyopathy). Summary In clinical practice, prepregnancy cardiac evaluation is mandatory, including evaluation of the clinical status, standard ECG (and 24–48 h monitoring, whenever required), and imaging, to define the individual risk profile. In presence of severe symptoms (advanced New York Heart Association class), cardiac dysfunction (moderate–severe reduced ejection fraction), haemodynamic load (left ventricular outflow tract obstruction, pulmonary hypertension), pregnancy is contraindicated. A tailored monitoring is warranted in other cases (mild–moderate risk pregnancies). Likewise, in women who develop PPCM, a risk stratification and tailored monitoring and therapy should be achieved by an expert, multidisciplinary team, including cardiologists, gynaecologists, obstetricians, genetic counsellor, and psychologists.

show abstract

A rare case of pregnancy with restrictive cardiomyopathy

Cited by 4 publications

References 5 publications

Disease features and management of cardiomyopathies in women

Disease features and management of cardiomyopathies in women

Intersection of Heart Failure and Pregnancy: Beyond Peripartum Cardiomyopathy

The challenge of cardiomyopathies and heart failure in pregnancy

Contact Info

Product

Resources

About