A rare case of primary pulmonary angiosarcoma

Alcid, Joel; Pinover, Wayne H.

doi:10.5348/z10-2018-47-cr

Cited by 1 publication

(2 citation statements)

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“…In the lung, primary angiosarcomas are extremely uncommon. The age of patients affected ranges between 22 to 79 years (mean, 54 years) with a male to female ratio of 3:1 [7]. Primary pulmonary angiosarcomas and metastatic angiosarcomas in the lung have similar symptomatology and radiologic features.…”

Section: Discussionmentioning

confidence: 99%

“…Immunotherapy with recombinant interleukin 2 in combination with either surgery or chemotherapy has also been shown to be effective. The use of radiation therapy in conjunction with surgery has resulted in local control and excellent functional and cosmetic outcome, for patients with angiosarcoma of the head and neck, but not the lung [7]. Clinical Case 20-year-old male with no significant past medical history other than a motor vehicle accident a year ago requiring a Thoracotomy who presents with a 4-month history of "in crescendo" left thoracic pain associated with hemoptysis and a10 kg weight loss.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Primary Pulmonary Angiosarcoma: A Case Report and Literature Review

Jordi¹,

Arturo²,

Sonia³

et al. 2020

J Med Res Surg

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Primary sarcomas of the thorax are rare. They are classified according to their histologic features and constitute a large group of tumors that occur in the lung, mediastinum, pleura, and chest wall. Although primary thoracic sarcomas commonly manifest as large, heterogeneous masses, they have a wide spectrum of radiologic manifestations, including solitary pulmonary nodules, central endobronchial tumors, and intraluminal masses within the pulmonary arteries. Angiosarcomas are rare, malignant vascular tumors, representing about 2% of all soft tissue sarcomas. The most frequently primarily affected sites include the heart, liver, breast, skin, and scalp, and they have a high rate of metastases to the lungs and, less commonly, liver, regional lymph nodes, and bone. Definitive diagnosis is made based on histopathological and immunohistochemical findings. No standard treatment regimen has been established for pulmonary angiosarcoma. Radiation therapy, chemotherapy, surgical resection, and immunotherapy have been attempted. The use of radiation therapy in conjunction with surgery has resulted in local control and excellent functional and cosmetic outcome, for patients with angiosarcoma of the head and neck, but not the lung. For advanced-stage disease, other than the combination of doxorubicin and ifosfamide-based regimens, there have been few other chemotherapeutic options for the treatment of local or metastatic angiosarcoma.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%