A rare case of primary leiomyoma of the vulva

Reyad, M. M.; Gazvani, M. R.; Khine, Myat Mon

doi:10.1080/01443610500419451

Cited by 21 publications

(16 citation statements)

References 4 publications

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“…2 This case is unique as fewer than 160 cases of smooth muscle tumours of the vulva have been reported in the literature. [2][3][4][5] Differentiating leiomyoma from atypical leiomyoma and leiomyosarcoma is challenging. Tavassoli and Norris have proposed the following diagnostic criteria for leiomyosarcoma: 9 • More than 5 cm in greatest dimension • Infiltrative margins • More than 5 mitotic figures per 10 HPF Nielsen et al studied clinicopathological features of 25 cases of smooth muscle tumours of vulva comprising of leiomyoma and five leiomyosarcoma.…”

Section: Discussionmentioning

confidence: 99%

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Leiomyoma of the vulva: a diagnostic challenge

Saxena

Goel

Sen³

2018

Int J Reprod Contracept Obstet Gynecol

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Smooth muscle tumours of vulva are rare and therefore can be missed clinically. Our patient, 48-year-old lady presented with lump in the left vulva that was clinically diagnosed as Bartholin duct cyst. The lumpectomy was done under local anaesthesia and the lesion was sent for pathological examination. On gross examination the mass was 3.5 cm in diameter. The microscopic examination revealed the lump to be leiomyoma and no necrosis or atypia was present. The final diagnosis of “vulval leiomyoma” was given. Postoperative period was uneventful, and the patient is on regular follow up and there has been no recurrence. Leiomyoma should be kept as a differential diagnosis when a lady presents in late reproductive age group with unilateral swelling in vulvar region which is firm in consistency and the lump must be sent for histopathological examination for definitive diagnosis and rule out malignancy. The pathologists play a critical role in recognition and management of smooth muscle tumors of the vulva and to rule out leiomyosarcoma.

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Section: Discussionmentioning

confidence: 99%

“…1 In literature there are limited reports of Leiomyoma vulva. [2][3][4][5] Identifying leiomyosarcoma in this region is difficult. It is important to diagnose malignancy due to the risk of recurrence as patients may need radiation and/or chemotherapy in addition to wide local excision and appropriate follow up.…”

Section: Introductionmentioning

confidence: 99%

Leiomyoma of the vulva: a diagnostic challenge

Saxena

Goel

Sen³

2018

Int J Reprod Contracept Obstet Gynecol

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“…Leiomyoma of vulva are being reported as a painless non tender labial nodule for last 50 years. [1][2][3][4] In case of 32 benign and malignant smooth muscle tumours 1 Department of Obstetrics & Gynaecology, DDU Hospital, New Delhi, India 2 Maulana Azad Medical College, Delhi, India of vulva, median age of patients was 35 years. 5 In present case, patient's age is 25 years.…”

Section: Discussionmentioning

confidence: 99%

Epitheloid leiomyoma of vulva: a diagnostic dilemma

Miglani¹,

Arora²,

Kadam³

et al. 2016

Int J Reprod Contracept Obstet Gynecol

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“…There are, however, leiomyomas that grow in unusual patterns and locations, making the diagnosis more challenging. There have been case reports reporting extrauterine leiomyomas arising from the gastrointestinal tract, genitourinary tract, as well as other rare locations including sinonasal cavities, orbits, and skin [5][6][7][8][9][10][11][12][13] . Abnormal growth patterns including retroperitoneal and parasitic growth have also been described, and tend to occur in women with a history of hysterectomy or surgery for uterine leiomyomas [4,14] .…”

Section: Discussionmentioning

confidence: 99%

Extrauterine myxoid leiomyoma mimicking an aggressive angiomyxoma

Chung

Hennedige

Sittampalam

et al. 2014

CRCP

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Introduction: Leiomyomas are benign smooth muscle tumours that usually arise from the uterus. Extrauterine leiomyomas are rare. We present a case of an extrauterine myxoid leiomyoma in a perimenopausal woman. Case:A 47-year-old woman presented with an increase in abdominal girth. Computed Tomography (CT) and Magnetic Resonance Imaging (MRI) scans revealed a large, lobulated, complex mass occupying the lower abdomen and pelvis with extension to the left ischiorectal fossa. An aggressive angiomyxoma (AAM) was considered as one of the differentials for this mass. Multiple attempts at radiological guided biopsy were performed, but with non-diagnostic yield. Intraoperatively, the mass encased the sigmoid colon, rectum, vaginal wall, and was adherent to bilateral pelvic sidewalls, pelvic floor, and left ischiorectal fossa. Enbloc resection of the mass, including an abdominoperineal resection and a total abdominal hysterectomy bilateral salpingo-oophrectomy (TAHBSO) was performed. Final histology showed features consistent with myxoid leiomyoma (ML). Conclusion:The radiological and pathological resemblance of ML and AAM presents a great diagnostic challenge. However, the actual diagnosis lies in the pathological analysis. Surgical resection with clear margins is the treatment of choice in the absence of a definite diagnosis. Prognosis of these tumours is generally good with low recurrence rates.

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A rare case of primary leiomyoma of the vulva

Cited by 21 publications

References 4 publications

Leiomyoma of the vulva: a diagnostic challenge

Leiomyoma of the vulva: a diagnostic challenge

Epitheloid leiomyoma of vulva: a diagnostic dilemma

Extrauterine myxoid leiomyoma mimicking an aggressive angiomyxoma

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