A Rare Case of Pyoderma Gangrenosum in a Patient With Pancreatic Neuroendocrine Tumor

Wesolow, Jacqueline

doi:10.7759/cureus.12343

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2022

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“…A vast range of haematological malignancies have also been associated with PG, including monoclonal gammopathy, myeloma, leukaemia, lymphoma and myelodysplasia 12 . PG as a paraneoplastic phenomenon has also been described in the literature, including in cancer and neuroendocrine tumours 17,18 .…”

Section: Systemic Associationsmentioning

confidence: 95%

Pyoderma gangrenosum: a review of the clinical, mechanistic and therapeutic landscape

Flora¹,

Frew²

2022

WPR

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Clinical featuresPG most commonly occurs on the lower extremities, although other areas, including the trunk, abdomen, scalp and face, may be affected. It may also affect extra-cutaneous locations, including the lungs, eyes and mouth (termed pyostomatitis vegetans) 3 . Up to 25% of patients affected with PG will experience 'pathergy' or the Koebner phenomenon 4 . This occurs when localised trauma causes worsening of existing PG or the formation of new PG lesions. The mechanism underlying

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Section: Systemic Associationsmentioning

confidence: 95%