2020
DOI: 10.4158/accr-2019-0402
|View full text |Cite
|
Sign up to set email alerts
|

A Rare Case of Rapidly Enlarging Myelolipoma in Sickle Cell Disease

Abstract: Objective: Adrenal myelolipoma (AM) is a benign tumor composed of mature fat cells and hemopoietic elements. Most AMs are incidental findings on imaging and clinically asymptomatic. The purpose of this case report is to describe a rare case of AM and explore its clinical manifestations, imaging features, and treatment. Methods: In this study, we report a case of a rapidly growing right AM in a patient with uncontrolled hemoglobin sickle cell disease. A 38-year-old male presented to our institution's endocrine … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
4
0

Year Published

2021
2021
2021
2021

Publication Types

Select...
1

Relationship

0
1

Authors

Journals

citations
Cited by 1 publication
(4 citation statements)
references
References 17 publications
0
4
0
Order By: Relevance
“…Many cases of adrenal myelolipoma have been reported in sickle cell disease (SCD) and thalassemia, but the pathogenesis is not clear [6,7]. However, it is postulated that the persistent anaemia in SCD may be responsible for the stimulation of metaplasia in the haemopoietic elements sited in the adrenal stroma, leading to rapid tumour growth [7,8]. This may explain why our patient developed the tumour in childhood,…”
Section: Discussionmentioning
confidence: 87%
See 3 more Smart Citations
“…Many cases of adrenal myelolipoma have been reported in sickle cell disease (SCD) and thalassemia, but the pathogenesis is not clear [6,7]. However, it is postulated that the persistent anaemia in SCD may be responsible for the stimulation of metaplasia in the haemopoietic elements sited in the adrenal stroma, leading to rapid tumour growth [7,8]. This may explain why our patient developed the tumour in childhood,…”
Section: Discussionmentioning
confidence: 87%
“…Mass-forming extramedullary haematopoiesis (EMH) is another type of fatcan occur in patients with haematologic disorders [8]. EMH is a physiological response secondary to insufficient blood cell production and bone marrow function and usually occurs in the reticulo-endothelial system outside the bone marrow.…”
Section: Fig 4 Gross Appearance Of the Tumourmentioning
confidence: 99%
See 2 more Smart Citations